Exhibit 10.15.1 AMENDMENT TO EMPLOYMENT AGREEMENT THIS AMENDMENT TO THE EMPLOYMENT AGREEMENT DATED FEBRUARY 5, 1996 ("the Amendment") is made and entered into this 1st day of February 2001 by and between SeraCare, Inc., a Delaware Corporation...

                                                               Exhibit 10.15.1

                       AMENDMENT TO EMPLOYMENT AGREEMENT


     THIS AMENDMENT TO THE EMPLOYMENT AGREEMENT DATED FEBRUARY 5, 1996 ("the
Amendment") is made and entered into this 1st day of February 2001 by and
between SeraCare, Inc., a Delaware Corporation (referred herein as the
("Corporation") and Xxxxx X. Xxxxx (the "Employee").

WHEREAS, the Corporation previously entered into an employment agreement on
February 5, 1996, (the "Employment Agreement");

AND WHEREAS the term of the Employment Agreement was previously extended by
the Board of Directors through February 5, 2002;

AND WHEREAS, the Corporation hereby wishes to amend the employment again;

AND WHEREAS the Employee wishes to have the employment agreement amended as
specified herein;

Now Therefore, the following extension and amendments are hereby agreed to by
both the Corporation and the Employee:

1.   The Term of the agreement has been extended through February 5, 2002.
2.   Effective February 1, 2001, the base annual compensation is hereby
     adjusted to be $300,000 per year plus an auto allowance of $750.00 per
     month.
3.   Employee shall receive 200,000 options with an exercise price of $3.25.
     Such options shall all have 7 year cliff vesting with accelerated
     vesting as follows;
         100,000 options will have accelerated vesting over two years
                 beginning with satisfactory achievement of the fiscal year
                 2002 business plan, half upon achievement of plan, other
                 half 1 year later.

         100,000 options will have accelerated vesting on the following
                 schedule;
                 10,000 options will vest immediately at the end of each
                 month that the closing price of the Company's stock is
                 $6.50 or greater for at least 10 trading days during the
                 month.

     All 200,000 options shall be accelerated in the event of a change of
control.

All other terms, conditions and provisions of the Employment Agreement shall
remain effective throughout the term of this Amendment.

I hereby certify that the above amendment was adopted by unanimous vote of the
Board of Directors on January 12, 2001.


                                       Hereby certified

                                       /s/ Xxxxx X. Xxxxxxx
                                       -------------------------------
                                       Xxxxx X. Xxxxxxx
                                       Corporate Secretary

                                       /s/ Xxxxx Xxxxx