FOURTH AMENDMENT TO SUBLEASE BETWEEN REGEN BIOLOGICS, INC. AND GENITOPE CORPORATION
Exhibit 10.1
THIS FOURTH AMENDMENT TO SUBLEASE (this “Fourth Amendment”) is made and entered into as of the
25th day of May, 2006, by and between REGEN BIOLOGICS, INC., a Delaware corporation
(“Regen”), and GENITOPE CORPORATION, a Delaware corporation (“Subtenant”).
R
E C I T A L S
This Fourth Amendment is made and entered into with reference to the following recitals:
A. Regen and Subtenant entered into a Sublease dated August 3, 1999, which was amended by a
Second Amendment to Sublease Agreement dated October 1, 2000, which amendment was styled as a
“second amendment” because Subtenant and Regen previously agreed to extend the term of the Sublease
and such extension was treated as a “first amendment”, as further amended by a Second Amendment to
Sublease dated February 25, 2002, as further amended by a Third Amendment to Sublease dated May
16, 2003 (collectively, as amended, the “Sublease”), for the sublease of approximately 7,655 square
feet of rentable area and 603 square feet of rentable common area (i.e. Subtenant’s share of common
area between Regen and Subtenant that is rentable area under the Master Lease) (the “Subleased
Premises”) in the building commonly known as “Building 12” of Seaport Center, and located at ▇▇▇
▇▇▇▇▇▇▇▇▇ ▇▇▇▇▇, ▇▇▇▇▇▇▇ ▇▇▇▇, ▇▇▇▇▇▇▇▇▇▇ ▇▇▇▇▇.
B. Regen and Subtenant wish to execute this Fourth Amendment to provide for an extension of
the term of the Sublease and to modify the base rent, operating expense and other related
provisions of the Sublease.
NOW, THEREFORE, in consideration of the foregoing, the sum of Ten Dollars ($10.00) and other
good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged,
Regen and Subtenant agree as follows:
1. Defined Terms. All defined terms herein shall have the meaning given to such term
in the Sublease or the Master Lease, as applicable, unless specifically defined herein.
2. Incorporation of Recitals. The foregoing recitals are incorporated by reference
into this Section 2 as if set forth in this Paragraph 2 in full.
3. Term. The term of the Sublease is extended and will expire on December 31, 2006,
unless sooner terminated or extended at the option of the Subtenant for up to a total of three (3)
one month extension periods, in accordance with the terms of the
Sublease. Commencing on January 1, 2007, the Subtenant will have the ongoing right to extend
the term of the Sublease for up to a total of three (3) one month extension periods by providing
written notice to Regen not less than forty five (45) days in advance of the then current Sublease
expiration date. In no event will the term of the Sublease extend beyond March 31, 2007.
4. Rent. Notwithstanding anything to the contrary in the Sublease, commencing on June
1, 2006 (the “Modified Rent Commencement Date”), and continuing through the term of the Sublease
(as extended by the terms of this Fourth Amendment), Subtenant shall pay base monthly rent (“Rent”)
in advance on the first day of each calendar month to Regen in the amounts specified below:
| Monthly Rate Per Rentable | ||||||||
| Period | Square Foot | Base Monthly Rent | ||||||
06/01/06 – 12/31/06 |
$1.75 | $14,451.50 | ||||||
If the Modified Rent Commencement Date and/or the last day of the Sublease term do not fall on
the first day of a month or the last day of a month, as applicable, the rent payable hereunder will
be pro-rated on a per day basis based on the actual number of days in such month. Commencing on
the Modified Rent Commencement Date, the foregoing rent payable by Subtenant under the terms of the
Sublease (as modified by the terms of this Fourth Amendment) shall be payable on a triple-net basis
and will not include any costs for real property taxes, Operating Expenses (as defined in the
Master Lease), janitorial services, utilities, garbage removal and the like, which costs will be
paid by Subtenant in accordance with the terms of Section 5 below.
5. Expenses. As of the Modified Rent Commencement Date, the pro-rata share of
Operating Expenses payable by Subtenant to Regen (the “Expense”) shall be calculated pursuant to
Section 5(a) of this Fourth Amendment, wherein Subtenant’s pro-rata share is based on the ratio of:
(i) the total square feet subleased by Subtenant pursuant to the Sublease to (ii) the total square
feet leased by Regen pursuant to the Master Lease.
(a) Expense Calculation. The expense shall be calculated by Regen, and Subtenant’s pro rata
share shall be invoiced to Subtenant on a monthly basis. Subtenant shall owe and pay to Regen its
pro-rata share of the Expense, such Expense to be calculated as follows: actual monthly Operating
Expenses billed to Regen by the Master Landlord, plus actual monthly operating expenses incurred by
Regen (including, without limitation, all Operating Expenses actually incurred by Regen), but not
billed by the Master Landlord, in relation to the Master Premises rented by Regen pursuant to the
Master Lease. Notwithstanding anything to the contrary contained in this Fourth Amendment,
Subtenant shall not be obligated to pay any monthly operating expenses or Operating Expense not
applicable to the Subleased Premises. The monthly expenses referred to herein will include
estimates of expenses reasonably anticipated to be incurred by Regen but not billed by Master
Lessor and Operating Expenses for such period, which will be adjusted at the end of each year
according to the Master Lease. Once the adjustments are received from the Master Landlord, Regen
shall provide a revised
- 2 -
statement to Subtenant showing such adjustments, together with, as appropriate, (i) an invoice
for the remaining amount due from Subtenant to Regen or (ii) a check for the refund amount due from
Regen to Subtenant. All such monthly invoices will be paid by Subtenant, together with the next
monthly Rent payment, and in no event later than thirty (30) days after receipt by Subtenant of
such invoices.
(b) Notwithstanding anything to the contrary contained in the Sublease, this Fourth Amendment
or the Master Lease, within ninety (90) days after receipt by Subtenant of Regen’s statement of the
Expense for any prior calendar year during the Term, Subtenant shall have the right, at Subtenant’s
sole cost and expense, upon ten (10) business days prior written notice, to inspect the applicable
books of Regen during the business hours of Regen at Regen’s office in the Building, or, at Regen’s
option, such other location as Regen reasonably may specify, for the purpose of verifying the
information contained in the statement, provided that the party inspecting such books is an
employee of a reputable accounting firm that provides a full range of accounting services that is
hired on a per-hour basis (and not on a contingency basis), and Subtenant uses reasonable efforts
to maintain the confidentiality of such audit and the results thereof. Unless Subtenant asserts
specific errors within ninety (90) days after receipt of the statement, the statement shall be
deemed correct as between Regen and Subtenant.
6. No Allowance. Regen and Subtenant agree that Regen will not be obligated to
provide any tenant improvement allowances whatsoever, or perform any work in the Premises, in
connection with the execution of this Fourth Amendment.
7. Approvals; Effectiveness. Regen and Subtenant agree that the effectiveness of this
Fourth Amendment is expressly conditioned on Regen’s receipt of Master Landlord’s written consent
to the terms of this Fourth Amendment (the “Approvals”). Regen shall use good faith reasonable
efforts to obtain the Approvals by May 31, 2006. If the Approvals are not obtained by Regen on or
before July 31, 2006 this Fourth Amendment will automatically terminate and be of no further force
and effect. If the Prime Lease Amendment is executed by Regen and Master Landlord, the following
provisions of the Prime Lease Amendment shall not be incorporated into the Sublease, as amended by
this Fourth Amendment: Section 3, 7, and 9.
8. Recapture. Commencing on August 31, 2006, Regen will have the ongoing right to
terminate the Sublease with respect to the office and common area portion of the Subleased
Premises, provided that Regen has delivered written notice to Subtenant (the “Recapture Notice”) of
such termination at least sixty (60) days prior to the date of such termination. The Recapture
Notice shall specify the date of termination (the “Recapture Termination Date”) and the applicable
portion of the Subleased Premises being recaptured by Regen and terminated under the Sublease (the
“Recaptured Premises”). If the Recaptured Premises does not constitute the entire Subleased
Premises and Regen elects to terminate the Sublease with respect to the Recaptured Premises then
(a) Subtenant shall vacate and tender the Recaptured Premises to Regen on the Recapture Termination
Date as if the Recapture Termination Date had
- 3 -
been originally set forth in the Sublease as the expiration date of the term of the Sublease
with respect to the Recaptured Premises, and (b) as to all portions of the Subleased Premises other
than the Recaptured Premises, this Sublease shall remain in full force and effect except that the
Rent, additional rent and the Expense payable pursuant to Section 5 of this Fourth Amendment shall
be reduced proportionately. If the Recaptured Premises does not constitute the entire Subleased
Premises, Regen shall pay all expenses of construction reasonably required to permit the operation
of the Recaptured Premises separate from the balance of the Subleased Premises.
9. Termination. Commencing on August 31, 2006, Subtenant will have the ongoing right
to terminate the Sublease with respect to the office and common area portion of the Subleased
Premises, provided that Subtenant has delivered written notice to Regen (the “Termination Notice”)
of such termination at least sixty (60) days prior to the date of such termination. The
Termination Notice shall specify the date of termination (the “Termination Date”) and the
applicable portion of the Subleased Premises being terminated by Subtenant and terminated under the
Sublease (the “Terminated Premises”). If the Terminated Premises does not constitute the entire
Subleased Premises and Subtenant elects to terminate the Sublease with respect to the Terminated
Premises then (a) Subtenant shall vacate and tender the Terminated Premises to Regen on the
Termination Date as if the Termination Date had been originally set forth in the Sublease as the
expiration date of the term of the Sublease with respect to the Terminated Premises, and (b) as to
all portions of the Subleased Premises other than the Terminated Premises, this Sublease shall
remain in full force and effect except that the Rent, additional rent and the Expense payable
pursuant to Section 5 of this Fourth Amendment shall be reduced proportionately. If the Terminated
Premises does not constitute the entire Subleased Premises, Subtenant shall pay all expenses of
construction reasonably required to permit the operation of the Terminated Premises separate from
the balance of the Subleased Premises.
10. Master Landlord’s Obligations. Notwithstanding anything to the contrary contained in the
Sublease (as amended by this Fourth Amendment), the following provisions of the Master Lease hereby
are incorporated into the Sublease, except that (i) references to “Landlord” shall mean only Master
Landlord, and (ii) “Landlord’s” obligations thereunder shall remain “Master Landlord Obligations”
as defined in Section 20(a) of the Sublease: Paragraphs 3(c), 3(d), 3(e), 3(f) and 3(g): Paragraph
6(a); Paragraph 13; and Paragraph 14. In the event of a conflict between the provisions of the
Master Lease (as amended by the Prime Lease Amendment), to the extent incorporated into the
Sublease and this Fourth Amendment, and the provisions of the Sublease as modified by this Fourth
Amendment, the provisions of the Sublease as modified by this Fourth Amendment shall control.
11. Hazardous Materials. Attached hereto as Exhibit A is a current list of Subtenant’s
Permitted Hazardous Materials and Hazardous Materials Plans. From time to time after the date of
this Fourth Amendment, but in no event more than two (2) times during each calendar year, Subtenant
may submit a proposed list of Subtenant’s Permitted Hazardous Materials to Regen. Regen shall use
commercially reasonable efforts to promptly approve or disapprove such proposed list, such approval
not to be
- 4 -
unreasonably withheld by Regen. In addition, Regen shall promptly submit such proposed list
to Master Landlord and request Master Landlord’s approval of same. Subtenant shall promptly
reimburse Regen for all costs and expenses incurred by Regen as a result of Regen submitting such
proposed list to Master Landlord for review. If Regen and Master Landlord consent to the proposed
list, then provided that Subtenant complies with the terms of the Master Lease (as incorporated by
the Sublease) related to such Permitted Hazardous Materials, Subtenant shall have the right to
bring such listed materials onto the Subleased Premises. However, until Regen and Master Landlord
approve such proposed list in accordance with the terms of this Fourth Amendment, Subtenant shall
not have any right to bring any Hazardous Materials onto the Subleased Premises. Regen shall not
be liable or responsible for Master Landlord’s failure to review and/or approve any proposed list
of Subtenant’s Permitted Hazardous Materials from Subtenant and if Master Landlord fails to review
or approve such list, the Sublease will continue in full force and effect without offset or
abatement of any sums payable by Subtenant. Notwithstanding anything to the contrary contained
in the Sublease, the Master Lease or this Fourth Amendment, Regen shall protect, indemnify, defend
upon demand with counsel reasonably acceptable to Subtenant, and hold harmless Subtenant and its
officers, directors, employees and agents from and against any and all liabilities, losses, claims,
actual out-of-pocket damages (excluding punitive or consequential damages (i.e., lost profits, lost
business opportunity), interest, penalties, fines, monetary sanctions, attorneys’ fees, experts’
fees, court costs, remediation costs, investigation costs, and other expenses arising from and
after the commencement date of the Sublease to the extent caused solely by the use, storage,
treatment, transportation, release or disposal of Hazardous Materials on or about the Premises by
Regen or Regen’s agents, employees or contractors.
12. Security Deposit. Regen and Subtenant acknowledge that as of the date of this Fourth
Amendment, Regen is holding Subtenant’s security deposit in the amount of $41,290.00.
13. No Other Amendment. Except to the extent expressly set forth in this Fourth
Amendment, the Sublease remains in full force and effect, without amendment, in accordance with its
terms.
14. Brokers. Each party hereto represents and warrants that it has dealt with no
broker in connection with this Fourth Amendment and the transactions contemplated herein between
Regen and Subtenant. Each party shall indemnify, protect, defend and hold the other party harmless
from all costs and expenses (including reasonable attorneys’ fees) arising from or relating to a
breach of the foregoing representation and warranty.
15. Authorization. The undersigned warrant that they have been authorized and
directed to execute this Fourth Amendment on behalf of their respective entities.
16. Counterparts. This Fourth Amendment may be signed in two or more counterparts,
each of which will be deemed an original and all of which shall constitute one agreement.
- 5 -
17. Titles. The titles of the sections and subsections of this Fourth Amendment are
for convenience of reference only and are not to be considered in construing this Fourth Agreement.
(Signature Page Follows)
- 6 -
IN WITNESS WHEREOF, the parties hereto have executed this Fourth Amendment as of the day and
year above written.
| REGEN: | ||||||
| REGEN BIOLOGICS,
INC., a Delaware corporation |
||||||
| By: Name: |
/s/ ▇▇▇▇▇ ▇. ▇▇▇▇▇
|
|||||
| Title: | Sr. VP and CFO | |||||
| SUBTENANT: | ||||||
| GENITOPE CORPORATION, | ||||||
| a Delaware corporation | ||||||
| By: Name: |
/s/ ▇▇▇ ▇. ▇▇▇▇▇▇, ▇▇.
|
|||||
| Title: | CEO | |||||
- 7 -
Exhibit A
Subtenant’s Permitted Hazardous Materials
Genitope Corporation
Chemical Inventory
| Reagent | Quantity | |
“Big Dye” |
< 500 ml. | |
0.5 M MgSO4 |
||
0.5M EDTA |
||
0.8% LE/TAE/EtBr gel |
||
1 M Imidazol |
||
1.2% LE/TAE/EtBr gel |
||
1.8% LE/TAE/EtBr gel |
||
10 mM Tris Cl |
||
10% Bleach |
<10 gal. | |
100 base pair ladder |
||
100% Ethanol |
< 20.0 Litre | |
100% IPA |
< 10.0 gal. | |
1000 base pair ladder |
< 25 ml. | |
100mM CoCl2 |
||
10mM GeneAmp dNTP blend |
||
10mM Tris Cl |
||
10x Carbonate Buffer |
||
10X PCR buffer for Taq |
||
10X PCR buffer II with MgCl2 |
||
10X Sodium Citrate |
||
1M CaCl2 |
||
1M KCl |
||
1M MgCl2 |
||
1M MOPS |
||
1M Na2CO3 |
||
1M Na-cacodylic acid in Tris-Cl |
||
1M NaHCO3 |
| Exhibit A Sublease | 1 | |||
| 525 Penobscot (Regen) |
Genitope Corporation
Chemical Inventory
| Reagent | Quantity | |
1M TRIS Cl ph7.8 |
||
1M TRIS Cl ph8.0 |
||
1M TRIS Cl ph8.5 |
||
1M NaCl |
||
1X Trypsin-EDTA Solution |
||
2% BSA/DPBS |
||
2% BSA/PBS |
||
2.2% LE/TAE/EtBr gel |
||
2.5% MetaPhore/TBE gel |
||
20X MOPS Running Buffer |
||
25mM Mg(OAc)2 solution |
||
2-Mercaptaethanol |
< 1.0 Litre | |
2mM dGTP-Na in H2O |
||
2 propanol |
< 2.5 L | |
3 M NaOAc |
||
3 M Sodium Acetate |
||
3M Tris |
||
4X SAF |
||
5% Nonfat Milk/DPBS |
< 500 ml | |
50 base pair ladder |
< 25 ml. | |
50X TAE |
||
5mM CoCl2 |
||
5X TBE |
||
5X XL Chelating Buffer |
||
5X XL RT buffer for RT-PCR |
||
70% Ethanol |
< 15 gal. | |
95% Ethanol |
< 15 gal. | |
ABTS |
< 25 ml. |
| Exhibit A Sublease | 2 | |||
| 525 Penobscot (Regen) |
Genitope Corporation
Chemical Inventory
| Reagent | Quantity | |
ABTS |
< 25 ml. | |
Acetic Acid, glacial |
< 4.0 gal. | |
Acetone |
< 1 gal. | |
Acetone |
< 1 gal. | |
Agar Strips Hycon TC |
< 500 ml. | |
Alcare |
< 500 ml. | |
Algicide |
< 500 ml. | |
Ammonium Acetate |
< 500 g | |
Ammonium Bifluoride, flake |
< 125 ml. | |
Ammonium Hydroxide |
||
AmpliTaq with MgCl2 and 10X rxn buffer II |
||
Anti-Rat IgG Heavy and Light |
||
ATCC Mycoplasma Detection Kit |
||
Azaserine |
< 1 L | |
Bacto Agar |
< 500 g | |
Bacto EC Medium |
< 500 g | |
Bacto Nzcym broth |
< 500 g | |
Bacto Sabouraud Dextrose Agar |
< 500 g | |
BCA Kit |
||
BCA Protein Assay Kit |
||
Bio-Rad Ready Gels |
||
BIS TRIS |
||
Bis-Tris |
||
Bleach |
< 5 gal. | |
Boric Acid Granular |
< 3 Kg | |
Brilliant Blue R |
< 5 grms | |
Brilliant Blue R 250 |
< 5 grms | |
Bromophenol Blue |
< 25 grms |
| Exhibit A Sublease | 3 | |||
| 525 Penobscot (Regen) |
Genitope Corporation
Chemical Inventory
| Reagent | Quantity | |
BSA |
< 200 grms | |
BSA |
< 200 grms | |
Buffer (Biphthalate) pH 4 |
< 250 grms | |
Buffer (Borate) pH 7 |
< 250 grms | |
Buffer (Phosphate) pH 10 |
< 250 grms | |
Buffer C1 |
||
Buffer P1 |
||
Buffer P3 |
||
Cacodylic Acid |
< 15 grms | |
Calcium Chloride Dihydrate |
< 500 ml. | |
CCM-I |
||
Cell Culture Media |
< 5.0 gal. | |
Cellgro-FREE Media |
< 5.0 gal | |
Chloroform |
< 2.0 gal, | |
CiDecon |
< 2.0 gal. | |
Clear Bath Algicide |
< 16 oz. | |
Cloned pfuDNA polymerase |
||
Cloned pfuDNA Polymerase rxn buffer |
||
Cobalt Chloride |
< 100 grms | |
Cobalt Chloride rxn buffer |
||
Coomasie Blue Staining Solution |
< 3.0 L | |
Coomassie Plus Protein Assay Reagent |
< 3.0 L | |
CyQuant |
||
DEPC |
||
Destaining Solution |
||
Dextrose Anhydrous, Powder |
< 500 grms | |
dGTP, Na-salt, PCR grade rxn buffer |
< 500 grms | |
Diethyl Pyrocarbonate |
< 1.0 Litre |
| Exhibit A Sublease | 4 | |||
| 525 Penobscot (Regen) |
Genitope Corporation
Chemical Inventory
| Reagent | Quantity | |
Dimethy Sulfoxide |
< 3.0 L | |
DMEM |
||
DMSO |
< 2.5 Litre | |
DMSO |
< 2.5 Litre | |
DNA H2O |
||
dNTP mix 10mM |
||
dPBS |
||
Dulbecco’s PBS |
||
EDTA, Disodium Salt, Dihydrate, Crystal |
||
EGTA |
< 500 grms | |
ELISA Wash Buffer 10X |
< 100 grms | |
Ethanol (200 proof) |
< 15 gal | |
Ethidium Bromide |
< 500 ml. | |
Ethylene Glycol |
< 500 ml. | |
EZ-Link Sulfo-NHS-LC-Biotin |
||
Fetal Bovine Serum (FBS), characterized |
||
Fetal Bovine Serum (FBS), dialyzed |
||
Ferric Citrate |
< 100 grms | |
Ferric Nitrate |
< 100 grms | |
Ferrous Sulfate |
< 250 grms | |
Ficoll 400 |
< 100 grms | |
Ficoll-Paque |
< 1.0 Litre | |
Fluorescien isothyocyanate |
< 100 grms | |
Formaldehyde (37%) |
< 600 ml | |
FuGENE |
||
Fyrite 7% CO2 |
< 1.0 Litre | |
Fyrite CO2 indicator refill |
< 1.0 Litre | |
Gel Drying Solution |
< 9.0 Litre |
| Exhibit A Sublease | 5 | |||
| 525 Penobscot (Regen) |
Genitope Corporation
Chemical Inventory
| Reagent | Quantity | |
Gel Extraction Kit (buffer EB,QG,PE) |
< 250 ml. | |
Gelatin |
< 100 grms | |
GeneAmp 25mM Mn(OAc)2 |
< 200 ml | |
Gentamicin |
< 500 ml. | |
Glucosamine |
||
Glutaraldehyde |
< 1.0 Litre | |
Glutaraldehyde (25%) |
< 1.0 Litre | |
Glycerol |
||
Glycine |
||
Goat Anti-Human IgG |
||
Goat anti-human IgG gamma chain |
||
Goat F(ab’)2 anti-human kappa light chain |
||
Goat F(ab’)2 anti-human lambda light antibody |
||
Growth check, microbial suspensions |
||
Guanidine |
||
Guanidium Isothyocyanate |
< 1.0 Litre | |
Hand Soap |
||
HEPES Free Acid |
< 500 grms | |
Hi Trap Lectin Test Kit |
< 10 ml. | |
High Pure Plasmid Isolation Kit |
< 500 ml. | |
Hightrap G Protein |
< 500 ml. | |
Hightrap SP |
< 500 ml. | |
Horseradish Peroxidase Avidin D |
< 500 ml. | |
Horseradish Peroxidase Substrate Kit |
< 500 ml. | |
Human IgG Kappa |
< 4 micro grms | |
Human IgG Lambda |
< 200 micro grms | |
Hybridoma SFM |
< 500 ml. | |
Hydrochloric Acid |
< 1.0 Litre |
| Exhibit A Sublease | 6 | |||
| 525 Penobscot (Regen) |
Genitope Corporation
Chemical Inventory
| Reagent | Quantity | |
Hydrocyanic Acid |
< 2.5 Litre | |
Hydrogen Peroxide 30% |
< 500 grms | |
Hypoxanthine |
< 25 grms | |
IEF Anode (lower) buffer |
||
IEF Cathode Buffer pH ▇-▇▇ |
||
▇▇▇ Sample Buffer pH 3-10 |
||
Imidazole |
< 500 grms | |
Imject Mariculture KLH in PBS |
< 100 mgrms | |
IPA |
< 4 gallons | |
IPA (100 %) |
< 4 gallons | |
Isoamyl Alcohols |
||
Isocetyl Alcohol |
||
Isopropyl Alcohol (70%) |
< 2.0 gal. | |
ISP Medium 2 |
||
Kanamycin |
< 5.0 gal | |
Kappa Control, characterized in-house IgG3 kappa conjugated to KLH |
||
Kappa Standard |
||
Kappa Standard Antibody, characterized in-house purified patient antibody |
||
Keyhole Limpet Hemocyanin (KLH) |
||
Kinetic Endotoxin Detection LAL Kinetic QCL |
||
Lactose, monohydrate |
< 100 grms | |
Laemmli Sample Buffer |
< 125 ml. | |
Lambda Control, characterized in-house IgG3 lambda conjugated to KLH |
||
Lambda Standard |
||
Lambda Standard Antibody, characterized in-house purified patient antibody |
||
LB Media |
||
L-Glutamine |
||
Liquid Nitrogen |
| Exhibit A Sublease | 7 | |||
| 525 Penobscot (Regen) |
Genitope Corporation
Chemical Inventory
| Reagent | Quantity | |
Lithium Chloride, Granular |
< 500 grms | |
Loading Dye |
||
LopHene |
< 4 gallons | |
Macro-Prep High Q Support |
< 200 ml. | |
Magnesium Acetate |
< 500 grms | |
Magnesium Chloride, 6-Hydrate, Crystal |
< 500 grms | |
Magnesium Sulfate |
< 1.0 Kgram | |
Maltose |
||
Manganese Chloride AR |
||
Mannopyranoside |
||
MEM Amino Acids |
||
Mercaptoethanol |
||
MetaPhor Agarose |
||
Methanol |
< 10.0 L | |
Methotrexate |
< 100 ml. | |
Methyl Mannopyranoside |
||
MilliQH2O |
||
Molecular Weight Standard |
||
Monoethanolamine |
< 500 ml. | |
MOPS |
< 1.0 Kgram | |
Mycoplamsa Kit |
||
NaCl, 0.9% |
||
NanoOrange Protein Kit |
||
▇▇▇▇ (▇.▇, ▇, ▇▇ ▇) |
< 200 ml. | |
Nickel Sulfate |
< 250 grms | |
Ni-NTA Agarose |
||
Ni-NTA Resin |
< 50 ml | |
NiSieve GTG Agarose |
< 500 ml. |
| Exhibit A Sublease | 8 | |||
| 525 Penobscot (Regen) |
Genitope Corporation
Chemical Inventory
| Reagent | Quantity | |
Nonfat Dry Milk |
< 500 grms | |
NuPAGE Bis-Tris gels 4-12% |
||
NuPAGE Bis-Tris Gels, 4-12% |
||
NuPAGE MES SDS Running Buffer |
||
NuPAGE MOPS SDS Running Buffer |
||
NuPAGE Sample Reducing Agent |
||
NuPAGE Transfer Buffer |
||
NuPAGE Tris-Acetate Gels, 3-8% |
||
NuSieve GTG agarose |
||
O-syl |
< 1 Gal. | |
PBS |
< 1 Gal. | |
PCR Purification Kit (buffer EB,PB,PE) |
||
Pepsin |
< 100 grms | |
Phenol, equilibrated |
< 100 grms | |
Phosphate Buffered Saline (PBS) |
< 5.0 Litre | |
Phosphoric Acid |
< 0.25 Litre | |
Pluronic L 121 |
< 1.0 Kgram | |
Polyoxyethylenesorbital Monolaurate |
< 100 ml. | |
Polysorbate 80 |
||
Potassium Acetate, granular |
< 500 grms | |
Potassium Chloride, Crystal |
< 500 grms | |
Potassium Hydroxide, Pellets |
< 1 Kgrms | |
Potassium Phosphate |
||
Precast Polyacrilamide Gel (Mini) |
||
Pre-diluted Protein Assay (BGG) |
||
Protein A Elution Buffer |
||
Protein A Wash Buffer |
||
Protein G Column |
| Exhibit A Sublease | 9 | |||
| 525 Penobscot (Regen) |
Genitope Corporation
Chemical Inventory
| Reagent | Quantity | |
Protein G Sepharose for Fast Flow |
< 5.0 ml. | |
Pyrosperse |
||
Qiagen Protease |
||
QIAquick PCR Purification Kit |
||
Quanti-cult |
||
RNA H2O |
||
RNAzol B |
< 1.5 Litre | |
RNeasy Maxi Kit |
< 2 Litre | |
RNeasy Midi Kit |
< 2 Litre | |
RNeasy Mini Kit |
< 2 Litre | |
Robane |
< 2.5 Kgrms | |
RO Water |
< 20 gallons | |
RPMI 1640 |
||
rTth DNA polymerase with buffer pack |
||
rTth XL DNA polymerase with buffer pack |
||
Sabouraud Dextrose Agar w/ Lecithin and Polysorbate 80 |
||
Saline (0.9%) |
||
Sargramostim Leukine |
||
SeaKem LE Agarose |
||
SeaPlaque GTG Agarose |
||
SeaPlaque GTG Agarose |
||
SFX-MAB |
||
Silver Nitrate |
||
Silver Xpress Silver Staining Kit |
||
Sodium Acetate, Trihydrate, Crystal |
< 1 Kgram | |
Sodium Azide |
< 100 grms | |
Sodium Bicarbonate, Powder |
< 1 Kgrms | |
Sodium Carbonate, Anyhdrous, Granular |
< 1 Kgrms |
| Exhibit A Sublease | 10 | |||
| 525 Penobscot (Regen) |
Genitope Corporation
Chemical Inventory
| Reagent | Quantity | |
Sodium Carbonate, Monohydrate, Crystal |
< 500 gams | |
Sodium Chloride, Crystals |
< 1.0 Kgrms | |
Sodium Citrate, Dihydrate, Granular |
< 500 ml. | |
Sodium Dodecyl Sulfate |
< 500 ml. | |
Sodium Hydroxide |
< 20 Liters | |
Sodium Nitroprusside |
< 25 grms | |
Sodium Phosphate, Dibasic, 7-Hydrate, Crystal |
< 500 gams | |
Sodium Phosphate, Monobasic, Monohydrate, Crystal |
||
Sodium Pyruvate |
||
Superblock Blocking Buffer in PBS |
||
TE Buffer |
||
Terminal Transferase |
||
TFBI |
||
TFBII |
||
Thymidine |
||
TMB Microwell Peroxidase Substrate |
||
Trace Klean |
||
Tricine |
< 250 grms | |
Tris Base |
< 3 Kgrms | |
TRIS Hydrochloride |
< 500 grms | |
Tris-Base |
||
Triton X-100 |
< 500 ml. | |
Trypan blue |
||
Trypsin |
||
Tryptic Soy Broth |
||
Trypticase Soy Agar |
||
Trypticase Soy Agar Plates |
< 500 ml. | |
Trypticase Soy Agar Slants |
< 500 ml. |
| Exhibit A Sublease | 11 | |||
| 525 Penobscot (Regen) |
Genitope Corporation
Chemical Inventory
| Reagent | Quantity | |
Tryptone Peptone |
< 500 ml. | |
Uridine |
< 1 gram | |
WFI |
||
Yeast Extract |
||
Zero Blunt TOPO PCR Cloning Kit |
< 1 ml |
| Exhibit A Sublease | 12 | |||
| 525 Penobscot (Regen) |