Exhibit 3
JOINT FILING AGREEMENT
The undersigned acknowledge and agree that the foregoing statement on Schedule
13D is filed on behalf of each of the undersigned and that all subsequent
amendments to this statement shall be filed on behalf of each of the undersigned
without the necessity of filing additional joint filing agreements. The
undersigned acknowledge that each shall be responsible for the timely filing of
such amendments, and for the completeness and accuracy of the information
concerning it contained therein, but shall not be responsible for the
completeness and accuracy of the information concerning the others, except to
the extent that it knows or has reason to believe that such information is
inaccurate.
This Agreement may be executed in counterparts and each of such counterparts
taken together shall constitute one and the same instrument.
EXECUTED this 1/st/ day of July, 2002.
/s/ Xxxx X. Xxxxxx
----------------------------------------
Xxxx X. Xxxxxx
/s/ Xxxxxxx X. Xxxxxx
----------------------------------------
Xxxxxxx X. Xxxxxx
/s/ Xxxxx X. XxXxx, Xx.
----------------------------------------
Xxxxx X. XxXxx, Xx.
/s/ Xxxxxx X. Xxxxxx
----------------------------------------
Xxxxxx X. Xxxxxx
/s/ Xxxxxx Xxxx
----------------------------------------
Xxxxxx Xxxx
ESSEX WOODLANDS HEALTH VENTURES
FUND IV, L.P.
By: Essex Woodlands Health Ventures IV,
L.L.C., general partner
By: /s/ Xxxxxx X. Xxxxxx
-------------------------------------
Name: Xxxxxx X. Xxxxxx
Title: Managing Director
VANGUARD VI, L.P.
By: Vanguard VI Venture Partners,
L.L.C., general partner
By: /s/ Xxxxxx X. Xxxxxx
-------------------------------------
Name: Xxxxxx X. Xxxxxx
Title: Member
VANGUARD VI AFFILIATES FUND, L.P.
By: Vanguard VI Venture Partners,
L.L.C., general partner
By: /s/ Xxxxxx X. Xxxxxx
-------------------------------------
Name: Xxxxxx X. Xxxxxx
Title: Member
H&Q HEALTHCARE INVESTORS
By: /s/ Xxx Xxxxxxx
-------------------------------------
Name: Xxx Xxxxxxx
Title: Treasurer
H&Q LIFE SCIENCES INVESTORS
By /s/ Xxx Xxxxxxx
--------------------------------------
Name: Xxx Xxxxxxx
Title: Treasurer