CYCLACEL PHARMACEUTICALS, INC.

Exhibit 10.1

CYCLACEL PHARMACEUTICALS, INC.

000 Xxxxxxx Xxxxx, Xxxxx 0000

Xxxxxxxx Xxxxxxx, XX 00000

January 14, 2021

Xx. Xxxxx Xxxxxxxx

c/o Cyclacel Pharmaceuticals, Inc.

000 Xxxxxxx Xxxxx, Xxxxx 0000

Xxxxxxxx Xxxxxxx, XX 00000

Dear Xx. Xxxxxxxx:

Reference is made to the agreement between us (the “Agreement”) made as of January 1, 2019. This will confirm our agreement to extend the Agreement through the period ended June 30, 2021, effective as of January 1, 2021. Please confirm your agreement to the foregoing by signing below in the space provided.

	Sincerely,
	CYCLACEL PHARMACEUTICALS, INC.
	By:	/s/ Xxxx XxXxxxxx
	Name:	Xxxx XxXxxxxx
	Title:	EVP, Finance & COO

ACKNOWLEDGED AND AGREED:

/s/ Xxxxx Xxxxxxxx

Xxxxx Xxxxxxxx