Contract
Exhibit 10.37
Confidential treatment has been requested for portions of this exhibit. The copy filed herewith omits the information subject to the confidentiality request. Omissions are designated as [*****]. A complete version of this exhibit has been filed separately with the Securities and Exchange Commission.
AMENDMENT NO. 2
TO THE
between
LONZA BIOLOGICS PLC
and
RELATING TO [**]
THIS AMENDMENT is made the 26th day of August 2002.
BETWEEN
1. | Lonza Biologics plc of 000 Xxxx Xxxx, Xxxxxx, XX0 0XX, Xxxxxxxxx, Xxxxxxx (“Biologics”) and |
2. | Xcyte Therapies Inc of 0000 Xxxxxxxx Xxxxxx, Xxxxx 000, Xxxxxxx, Xxxxxxxxxx 00000, XXX (“Customer”). |
WHEREAS
A. | The parties have entered into an Agreement dated 6th June 2000 (as amended) relating to the supply of Services (as therein defined), and |
B. | The parties now wish to amend the terms of the Agreement |
THEREFORE it is hereby agreed by and between the parties that the Agreement shall be amended as follows: -
1. | Stage 14 shall be added to Schedule 2 as follows: |
“14.0 | Stage 14 – Production of cGMP Product at [**] |
14.1 | Objectives |
14.1.1 | To manufacture [**] from a [**] in accordance with the principles of current Good Manufacturing Practice (cGMP). |
14.2 | Activities |
14.2.1 | Review status of GMP documentation for GMP manufacture of Product. |
14.2.2 | Recover [**] from the MCB and [**] to [**]. |
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[*] | Certain information on this page has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions. |
14.2.3 | Carry out [**] at [**]. |
14.2.4 | Clarify [**] as specified. |
14.2.5 | [**] by the [**] established. |
14.2.6 | Test [**] against the current [**]. |
14.2.7 | Undertake quality assurance review of lot documentation and issue a [**]. |
14.2.8 | Make [**] available to the Customer ex-works with the documents associated with the [**]. |
14.3 | Timescale |
Stage 6 will be complete upon issue of the [**] (activity 6.2.7) for the [**]. It is estimated that the [**] for the [**] will be issued [**] from commencement of the batch. “ |
2. | Schedule 3, Part 1 shall be amended as follows: |
“14 | Production of cGMP Product at [**] £[**]” |
3. | Schedule 3, Part 2 Price shall be amended as follows: |
“2.4 | For Stage 14 |
“[**] upon completion of Stage” |
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[*] | Certain information on this page has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions. |
As witness the hands of the duly authorized representatives of the parties hereto, the day and year first before written. |
Signed by | ||
for and on behalf of Xcyte Therapies Inc. | /s/ Xxxxxx X. Xxxxxxxx | |
Signed by | ||
for and on behalf of Lonza Biologics plc. | /s/ Xxxxx Xxxxxx |
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