Exhibit 10.8
March 18, 1996
Xxxx Xxxxxx, M.D.
Boston Life Sciences
Reservoir Place
0000 Xxxxxxx Xxxx
Xxxxxxx, XX 00000
RE: License Agreement Dated 3/15/93
Amendment to Add Patent Application to Appendix B
Dear Marc,
In accordance with Paragraph 8.3 of the Sponsored Research Agreement between
Xxxxxxx Pharmaceuticals, Inc. and Children's Medical Center Corporation dated
3/15/93, the Appendix B of the License Agreement between the same parties and of
even date is hereby amended to include the following patent application:
CMCC 518 "Pharmaceutical Compositions Comprising Troponin Subunits, Fragments
and Analogs Thereof and Methods of Their Use to Inhibit Angiogenesis" by Xxxxxx
X. Xxxxx, Xxxxxx X. Xxxxxx, Xxxxxxx Weidershain, Inmin Wu, and Arthus Sytkowski,
filed February 16, 1996.
Sincerely,
/s/ Xxxxxxx New
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Xxxxxxx New
Vice President for Research Administration
Agreed for XxxXxxx Pharmaceuticals, Inc.
/s/ Xxxx Xxxxxx
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Xxxx Xxxxxx
