AGREEMENT

   1

                                                            Exhibit 1

                                    AGREEMENT

       Pursuant to Rule 13d-1-(k)(1) under the Securities Exchange Act of 1934,
the undersigned hereby agree that only one statement containing the information
required by Schedule 13G need be filed with respect to the ownership by each of
the undersigned of shares of stock of Genomica Corporation.

       This Agreement may be executed in any number of counterparts, each of
which shall be deemed an original.


Dated: February 12, 2001                    ARCH VENTURE FUND III, L.P.

                                            By:  ARCH Venture Partners, L.L.C.
                                                 its General Partner


                                                 By:              *
                                                     ---------------------------
                                                     Xxxxxx Xxxxxxx
                                                     Managing Director


                                            ARCH VENTURE PARTNERS, L.L.C.


                                                 By:              *
                                                     ---------------------------
                                                     Xxxxxx Xxxxxxx
                                                     Managing Director


                                                          *
                                            -----------------------------
                                              Xxxxxx Xxxxxxx

                                                          *
                                            -----------------------------
                                              Xxxxx Xxxxxxxx

                                                          *
                                            -----------------------------
                                              Xxxxxx Xxxxxx

                                                          *
                                            -----------------------------
                                              Xxxxxxx Xxxxx

                                                     * By: /s/ Xxxx XxXxxxxxx
                                                          ----------------------
                                                           Xxxx XxXxxxxxx as
                                                           Attorney-in-Fact


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This Agreement was executed by Xxxx XxXxxxxxx pursuant to Powers of Attorney
attached hereto as Exhibit 2 and incorporated herein by reference.





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