Tel: +44 (0)1223 497400 Fax: +44 (0)1223 497461 cambridge@f-star.com F-star Therapeutics Limited Eddeva B920 Babraham Research Campus Cambridge CB22 3AT United Kingdom

Exhibit 10.1

	Tel: x00 (0)0000 000000
	Fax: x00 (0)0000 000000
	xxxxxxxxx@x-xxxx.xxx
	F-star Therapeutics Limited
	Eddeva B920
	Babraham Research Campus
	Xxxxxxxxx
	XX00 0XX
	Xxxxxx Xxxxxxx
	xxx.x-xxxx.xxx

STRICTLY PRIVATE & CONFIDENTIAL

Xxxxx Xxxxxxx

Addresses

6 April 2022

Dear Eliot

Amendment to Service Agreement

I am writing to confirm an Amendment to your Service Agreement with effect from 31 March 2022.

The parties hereby agree as follows:

1.Section 18.6 of the Service Agreement is amended by deleting the reference to, “to the extent not assumed by an acquirer”.

2.Except as specifically modified herein, any of the other terms of the Agreement shall remain in full force and effect.

In witness whereof, the parties hereto have executed the Amendment as of the date first written above.

For F-star Therapeutics Ltd			For Employee
Signature:	/s/ Xxxxxxx Xxxxxxx-Xxxxx		Signature:	/s/ Xxxxx X. Xxxxxxx
Name:	Xxxxxxx Xxxxxxx-Xxxxx		Name:	Xxxxx Xxxxxxx
Title:	Chief Financial Officer		Title:	Chief Executive Officer

F-star Therapeutics Limited Eddeva B920 | Babraham Research Campus | Xxxxxxxxx, XX00 0XX, XX | T: x00 0000 000000 | xxx.x-xxxx.xxx