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Exhibit 10.18
AMENDMENT 1
This Amendment dated the ___ day of ________, 1996 is hereby incorporated in
its entirety into that certain Development and License Agreement between
Recordati S.A. Chemical and Pharmaceutical Company ("Recordati") and Ascent
Pediatrics, Inc. ("Ascent") dated October 8, 1996 (the "Agreement").
Pursuant to Section 9.9 of the Agreement, the parties hereby amended the
Agreement by deleting Australia and Canada from the list of "Major Countries"
in Exhibit B of the Agreement.
Agreed & Accepted:
Recordati S.A. Chemical Ascent Pediatrics, Inc.
and Pharmaceutical Company
By: /s/ Luciano Boccasso By: /s/ Xxxxxx Xxxxxxxx
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Name: Luciano Boccasso Name: Xxxxxx Xxxxxxxx
Title: President Title: Chairman
Date: Date: February 28, 1997
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