AGREEMENT OF JOINT FILING

AGREEMENT OF JOINT FILING

This joint filing agreement (this “Agreement”) is made and entered into as of this 13th day of October 2016, by and among TPG Group Holdings (SBS) Advisors, Inc., TPG Advisors VI, Inc., TPG Advisors V, Inc., TPG Biotech Advisors, Inc., Xxxxx Xxxxxxxxx and Xxxxx X. Xxxxxxx.

The parties to this Agreement hereby agree to prepare jointly and file timely (and otherwise to deliver as appropriate) all filings on any Form 3, Form 4, Form 5 or Schedule 13D or Schedule 13G, and any and all amendments thereto and any other document relating thereto (collectively, the “Filings”) required to be filed by them pursuant to the Securities Exchange Act of 1934, as amended.  Each party to this Agreement further agrees and covenants to the other parties that it will fully cooperate with such other parties in the preparation and timely filing (and other delivery) of all such Filings.

This agreement may be executed in any number of counterparts, each of which shall be deemed to be an original, but all of which together shall constitute one and the same instrument.

IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first set forth above.

Dated:  October 13, 2016

TPG Group Holdings (SBS) Advisors, Inc.

By: /s/ Xxxxxxx XxXxxxx                                      

Name:  Xxxxxxx XxXxxxx

Title:    Vice President

TPG Advisors VI, Inc.

By: /s/ Xxxxxxx XxXxxxx                                      

Name: Xxxxxxx XxXxxxx

Title:    Vice President

TPG Advisors V, Inc.

By: /s/ Xxxxxxx XxXxxxx                                      

Name: Xxxxxxx XxXxxxx

Title:    Vice President

TPG Biotech Advisors, Inc.

By: /s/ Xxxxxxx XxXxxxx                                      

Name: Xxxxxxx XxXxxxx

Title:    Vice President

Xxxxx Xxxxxxxxx

By: /s/ Xxxxx Xxxx                                               

Name: Xxxxx Xxxx, on behalf of Xxxxx Xxxxxxxxx (1)

Xxxxx X. Xxxxxxx

By: /s/ Xxxxx Xxxx                                               

Name: Xxxxx Xxxx, on behalf of Xxxxx X. Xxxxxxx (2)

_______________

(1) Xxxxx Xxxx is signing on behalf of Xx. Xxxxxxxxx pursuant to an authorization and designation letter dated June 19, 2015, which was previously filed with the Securities and Exchange Commission (the “Commission”) as an exhibit to an amendment to Schedule 13D filed by Xx. Xxxxxxxxx on June 22, 2015 (SEC File No. 005-87680).

(2) Xxxxx Xxxx is signing on behalf of Xx. Xxxxxxx pursuant to an authorization and designation letter dated June 19, 2015, which was previously filed with the Commission as an exhibit to an amendment to Schedule 13D filed by Xx. Xxxxxxx on June 22, 2015 (SEC File No. 005-87680).