April 17, 2018 William (Obi) Greenman c/o Cerus Corporation

Exhibit 10.1

April 17, 2018

Xxxxxxx (Obi) Xxxxxxxx

c/o Cerus Corporation

0000 Xxxxxxxx Xxxxx

Xxxxxxx, XX 00000

Dear Obi,

The purpose of this letter is to amend the terms of your Employment Letter Agreement with Cerus Corporation dated May 12, 2011 (as amended on December 5, 2012, the “Agreement”) to provide that any acceleration of vesting benefit to which you are entitled pursuant to the Agreement shall apply to all equity awards then held by you and not solely to your stock options.

Specifically, the language that provides for accelerated vesting shall be revised to read as follows:

“accelerated vesting of any unvested shares subject to any outstanding equity awards such that all shares subject to your equity awards will be fully vested (and immediately exercisable, as applicable) effective as of the employment termination date.”

Please sign below to indicate your acceptance of this amendment of the Agreement.

Sincerely,

/s/ Xxxxxxxx Xxxxxx

Xxxxxxxx Xxxxxx

Chief Legal Officer and General Counsel

Approved and Accepted

/s/ Xxxxxxx X. Greenman________

Xxxxxxx (Obi) Xxxxxxxx

Date April 17, 2018_____________