EXHIBIT 1
JOINT FILING AGREEMENT PURSUANT TO RULE 13d-1(k)(1)
The undersigned acknowledge and agree that the foregoing statement on Schedule
13G is filed on behalf of each of the undersigned and that all subsequent
amendments to this statement on Schedule 13G shall be filed on behalf of each of
the undersigned without the necessity of filing additional joint filing
statements. The undersigned acknowledge that each shall be responsible for the
timely filing of such amendments, and for the completeness and accuracy of the
information concerning him, her or it contained herein, but shall not be
responsible for the completeness and accuracy of the information concerning the
other entities or persons, except to the extent that he, she or its knows or has
reason to believe that such information is inaccurate.
XXXXXXXX VENTURE MANAGERS INC.
By: Its Director and Vice President,
/s/ Xxxx Xxxx
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Signature
Xxxx Xxxx, Authorized Signatory
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Name/Title
XXXXXXXX VENTURE MANAGERS LIMITED
By: Its Director,
/s/ Xxxx Xxxx
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Signature
Xxxx Xxxx, Authorized Signatory
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Name/Title
XXXXXXXX VENTURES INTERNATIONAL LIFE
SCIENCES FUND II L.P.1
By: Xxxxxxxx Venture Managers, Inc.,
its General Partner
/s/ Xxxxxxx Xxxxx /s/ Xxxx Xxxx
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Signature
Xxxxxxx Xxxxx, Xxxx Xxxx, Authorized
Signatories
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Name/Title
XXXXXXXX VENTURES INTERNATIONAL LIFE
SCIENCES FUND II L.P.2
By: Xxxxxxxx Venture Managers, Inc.,
its General Partner
/s/ Xxxxxxx Xxxxx /s/ Xxxx Xxxx
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Signature
Xxxxxxx Xxxxx, Xxxx Xxxx, Authorized
Signatories
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Name/Title
XXXXXXXX VENTURES INTERNATIONAL LIFE
SCIENCES FUND II L.P.3
By: Xxxxxxxx Venture Managers, Inc.,
its General Partner
/s/ Xxxxxxx Xxxxx /s/ Xxxx Xxxx
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Signature
Xxxxxxx Xxxxx, Xxxx Xxxx, Authorized
Signatories
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Name/Title
SITCO NOMINEES LTD. VC 01903 AS NOMINEE
OF XXXXXXXX VENTURES INTERNATIONAL
LIFE SCIENCES FUND II GROUP CO-
INVESTMENT SCHEME
By: SITCO Nominees Ltd. VC 01903
/s/ Xxxxxxx Xxxxx /s/ Xxxx Xxxx
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Signature
Xxxxxxx Xxxxx, Xxxx Xxxx, Authorized
Signatories
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Name/Title
XXXXXXXX VENTURES INTERNATIONAL LIFE
SCIENCES FUND II STRATEGIC PARTNERS L.P.
By: Xxxxxxxx Venture Managers Inc.,
its General Partner
/s/ Xxxxxxx Xxxxx /s/ Xxxx Xxxx
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Signature
Xxxxxxx Xxxxx, Xxxx Xxxx, Authorized
Signatories
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Name/Title
SV (NOMINEES) LIMITED AS NOMINEE OF
XXXXXXXX VENTURES INVESTMENTS LIMITED
By: SV (Nominees) Limited
/s/ Xxxxxxxx XxXxxxx
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Signature
Xxxxxxxx XxXxxxx, Authorized Signatory
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Name/Title