Amendment No. 2 to the License Agreement between Johns Hopkins University and Sangamo BioSciences, Inc.

Exhibit 10.9

Amendment No. 2

to the License Agreement between

Xxxxx Xxxxxxx University and Sangamo BioSciences, Inc.

This Amendment No. 2, dated July 26, 1999 (“Effective Date”) to the License Agreement dated June 29, 1995 concerning the licensing and other matters of patent properties referred to in Appendix A of the License Agreement, and in Amendment No. 1 dated June 1, 1998 (Xx. Xxxxxxxxxx Xxxxxxxxxxxxxx, Inventor) and other Patent Rights, is entered into between Xxxxx Xxxxxxx University, a not-for-profit educational institution having an address at 0000 Xxxxx Xxxxxxx Xxxxxx, Xxxxxxxxx, Xxxxxxxx (“XXXXX XXXXXXX” or “JHU”) and Sangamo BioSciences, Inc., a corporation of the State of Delaware and having a principal place of business at Point Richmond Tech Center, 000 Xxxxx Xxxx., Xxxxx X000, Xxxxxxxx, XX 00000 (“LICENSEE”).

This document amends the License Agreement by the following:

1. In Article XIV, line 1, change it to read, “Any payment, notice or other communications pursuant to this Agreement shall be sufficiently made or given on the date of mailing if sent to such party by certified first class mail, postage prepaid, addressed to it at its address below or as it shall designate by written notice given to the other party:

In the case of XXXXX XXXXXXX:

Xxxx X. Xxxxxxx, C.F.A.

Director, Office of Technology Transfer

XXXXX XXXXXXX UNIVERSITY

708N Xxxxx Xxxx Center

0000 Xxxxx Xxxxxxx Xxxxxx

Xxxxxxxxx, Xxxxxxxx 00000-0000

Phone: (000) 000-0000

Fax: (000) 000-0000

2. Except as expressly modified by this Amendment No. 2, the License Agreement and Amendment No. 1 shall remain in full force and effect.

IN WITNESS WHEREOF, the parties have caused this Amendment to be duly executed and delivered as of the date first written above.

For Sangamo BioSciences, Inc.:
/s/ Xxxxxx X. Xxxxxxxx XX				August 15, 1999
Xxxxxx X. Xxxxxxxx XX				Date
President

1

For Xxxxx Xxxxxxx University:
/s/ Xxxxxxxx X. Xxxxxxx, Ph.D.				July 26, 1999
Xxxxxxxx X. Xxxxxxx, Ph.D.				Date
Vice Xxxxxxx for Research

2