FIFTH AMENDMENT TO SECURED CREDIT AGREEMENT

Exhibit 10.48

FIFTH AMENDMENT TO SECURED CREDIT AGREEMENT

FIFTH AMENDMENT TO SECURED CREDIT AGREEMENT dated as of December 22, 2021 (this “Amendment”), by and among AiPharma Global Holdings LLC, a Delaware limited liability company (“DE Topco”), AIPHARMA HOLDINGS LIMITED, a company formed under the laws of the British Virgin Islands (“BVI Holdco”), and AIPHARMA ASIA LIMITED, a company formed under the laws of Hong Kong (“HK Opco” and together with DE Topco and BVI Holdco, individually and collectively, the “Borrower”), and Aditxt, Inc., a Delaware corporation (the “Lender”).

RECITALS

A. Lender made a loan to Borrower pursuant to a Secured Credit Agreement, dated as of August 27, 2021 (as the same has been and may be amended, supplemented or otherwise modified from time to time, the “Credit Agreement”).

B. Lender and Borrower desire to amend the Credit Agreement on the terms set forth herein.

In consideration of the mutual covenants and agreements herein contained and contained in the Transaction Agreement, the parties hereto agree as follows:

1. Defined Terms. Any and all initially capitalized terms used in this Amendment (including, without limitation, in the Recitals to this Amendment) without definition shall have the respective meanings assigned thereto in the Credit Agreement, or if not defined therein, as defined in the Transaction Agreement.

2. Amended Defined Terms. The following defined terms, as set forth in Section 1.01 of the Credit Agreement, are hereby amended and restated in their entirety to read as follows:

“Maturity Date” means December 31, 2022.

3. Miscellaneous Provisions. The provisions of Article VIII of the Credit Agreement are incorporated herein by this reference mutatis mutandis.

[Signature page follows]

IN WITNESS WHEREOF, the parties hereto have caused this Amendment to be duly executed by their respective authorized officers as of the day and year first above written.

	AIPHARMA GLOBAL HOLDINGS LLC,
	a Delaware limited liability company
	By:	/s/ Xxxxxxxxxx Xxxxxxx
	Name:	Xxxxxxxxxx Xxxxxxx
	Title:	Legal Representative / CEO
	AIPHARMA HOLDINGS LIMITED,
	a company formed under the laws of the British Virgin Islands
	By:	/s/ Xxxxxxxxxx Xxxxxxx
	Name:	Xxxxxxxxxx Xxxxxxx
	Title:	Legal Representative / CEO
	AIPHARMA ASIA LIMITED,
	a company formed under the laws of Hong Kong
	By:	/s/ Xxxxxxxxxx Xxxxxxx
	Name:	Xxxxxxxxxx Xxxxxxx
	Title:	Legal Representative / CEO
	ADITXT, INC.,
	a Delaware corporation
	By:	/s/ Amro Xxxxxxx
	Name:	Amro Xxxxxxx
	Title:	CEO