Loan Agreement Between 667, L.P and Baker Bros. Advisors LP

Exhibit 99.1

Loan Agreement Between 667, L.P and Xxxxx Bros. Advisors LP

For value received, Xxxxx Bros. Advisors LP (the “Management Company”) promises to pay 667, L.P. (“667”), the amounts set forth in Schedule A below, payable on the Due Date (as defined below) with interest payable through the Due Date (as defined below) at a rate of 4.55% annually.

667 is lending the Management Company these amounts so that Xxxxxx Xxxxx, as agent of the Management Company, may exercise 15,000 Incyte Corporation (“INCY”) Director’s Non-qualified Stock Options at $49.01 per share (the “Shares”) and deposit the Shares into Xxxxxx Xxxxx’x brokerage account held at JPMorgan.

The “Due Date” shall be May 7, 2054, however, following the sale by Xxxxxx Xxxxx of all of the Shares, the Due Date shall accelerate to the date that is 10 days after date of the last sale of Shares.

This Loan Agreement shall be construed in accordance with the laws of the State of New York.

Xxxxx Bros. Advisors LP

/s/ Xxxxxxxxx X. Xxxxxx

/s/ Xxxxxxxxx X. Xxxxxx

By: Xxxxxxxxx X. Xxxxxx, Chief Financial Officer

667, L.P.

By: Xxxxx Bros. Advisors LP, management company and investment adviser to 667, L.P., pursuant to authority granted to it by Xxxxx Biotech Capital, L.P., general partner to 667, L.P., and not as the general partner.

/s/ Xxxxx X. Xxxxxxx

Xxxxx Xxxxxxx

President

Schedule A

Fund		667, L.P.
Loan		$	55,918