Iowa State University Research Park Corporation

Exhibit 10.108

Iowa State University Research Park Corporation

0000 Xxxxx Xxxx Xxxxx, Xxxxx 0000

Xxxx, Xxxx 00000-0000

Memorandum of Agreement

DATE: February 12, 2015

TO: Xxxx Xxxxxxx, CFO

NewLink Genetics Corporation

0000 X. Xxxx Xxxxx, Xxxxx 0000

Xxxx, XX 00000

FROM: Xxxxxx X. Xxxxxx, President

RE: ADDENDUM TO THE LEASE BETWEEN ISU RESEARCH PARK CORPORATION AND NEWLINK GENETICS CORPORATION DATED MARCH 1, 2010.

The following information constitutes changes to the Lease Agreement between ISU Research Park Corporation (Landlord) and NewLink Genetics Corporation (Tenant). Upon signatures of appropriate representatives of Landlord and Tenant affixed to this Memorandum, this Memorandum becomes a part of that Lease Agreement dated March 1, 2010.

Tenant has requested and Landlord agrees to extend the Lease Agreement for Suites 5100- 5400 (±23,544 rentable square feet), Building #5 at 0000 Xxxxx Xxxx Xxxxx, in the following manner:

Sq. Ft. Sq. Ft. Monthly Monthly Annual Annual

Base Operating Base Operating Base Operating

Term Rents Rents Rents Rents Rents Rents

2/1/2015-

1/31/2020 $11.50 Actual $22,563.00 Actual $270,756.00 Actual

Exhibit 10.108

NewLink Genetics Corporation

Page Two

February 12, 2015

Tenant leases the space as is. Any modifications will be at the Tenant’s sole expense. Tenant will continue to be responsible for all utility costs and operations. Subject to the terms of this Memorandum, Tenant agrees that all terms and conditions of the March 1, 2010 Lease and those described in this Memorandum shall remain in force.

Please sign and return both originals to my office if you concur with the above terms. We will then send a fully executed copy for your records.

AGREED

FOR FOR

NewLink Genetics Corporation ISU Research Park Corporation

/s/Xxxx Xxxxxxx                    /s/Xxxxxx Xxxxxx

VP Finance Director

Title

Title

2/12/2015                        2/12/2015

Date Date