December 8, 2000 Advanced Viral Research Corp. 200 Corporate Blvd. South Yonkers, NY 10701 Gentlemen: Please be advised that we have been assigned the rights of the Investor contained in the Equity Line of Credit Agreement (the "Agreement") dated...

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                                                                   EXHIBIT 10.44

                                GMF HOLDINGS INC.
                               00 XXXXXXXXX XXXXXX
                                 XXXXXX BAHAMAS

                                December 8, 2000


Advanced Viral Research Corp.
000 Xxxxxxxxx Xxxx. Xxxxx
Xxxxxxx, XX 00000

Gentlemen:

         Please be advised that we have been assigned the rights of the Investor
contained in the Equity Line of Credit Agreement (the "Agreement") dated
September 18, 2000 between Spinneret Financial Systems Ltd. and Advanced Viral
Research Corp. (the "Company").

         By this letter we hereby waive any rights to assign our interest in the
Agreement . Very truly yours, GMF HOLDINGS INC.

                                            By: /s/ Xxxxx Xxxxx
                                                ----------------------------
                                            Name: Xxxxx Xxxxx
                                            Title: President