AMENDED AND RESTATED SECURITY AGREEMENT

EXHIBIT 10.10

This Amended and Restated Security Agreement, dated as of January 2, 2024 (the “Agreement”) is made by and among Renovaro BioSciences Inc., a corporation duly organized and validly existing under the laws of Delaware (the “Company”) and Paseco ApS, a limited company organized under the Kingdom of Denmark (“Paseco”), and RS Bio ApS (“RS Bio,” and together with Paseco, the “Secured Parties”).

WHEREAS, effective December 30, 2022, Paseco and the Company entered into that certain Security Agreement (the “Original Agreement”) to secure the obligations of the Company under certain promissory notes issued to Paseco (the “Paseco Notes”), of which $3,000,000 in principal amount remains outstanding;

WHEREAS, on each of November 3, 2023 and January 2, 2024, RS Bio received 5% Original Issue Discount Promissory Notes from the Company in an aggregate principal amount of $1,526,315 (the “RS Bio Notes”, and together with the Paseco Notes, the “Notes”);

WHEREAS, the Company has requested that Paseco amend and restate the Original Agreement to provide for security of the RS Bio Notes and Paseco has agreed to amend and restate the Original Agreement in accordance with Section 5.04 of the Original Agreement.

NOW THEREFORE, in order to induce the Secured Parties to extend the loans evidenced by the Paseco Notes and RS Bio Notes, and for other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the Company has agreed to pledge and grant a continuing security interest in the Collateral (as hereinafter defined) as security for the Secured Obligations (as hereinafter defined). Accordingly, the parties hereto agree as follows:

Section 1. Definitions. Each capitalized term used herein and not otherwise defined shall have the meaning assigned to such term in the Note. In addition, as used herein:

“Collateral” shall have the meaning ascribed thereto in Section 3 hereof.

“Event of Default” shall have the meaning ascribed thereto in Section 5 of the February Notes, as amended and restated, and as set forth in Section 6 of the March Note, as amended.

“Secured Obligations” shall mean, collectively, the principal of and interest on the Paseco Notes and RS Bio Notes issued by the Company and held by the Secured Parties, and all other amounts from time to time owing to the Secured Parties by the Company under this Agreement, the Paseco Notes and the RS Bio Notes.

“Secured Parties” shall have the meaning defined in the preamble to this Agreement; provided, that such term also shall include, as to the benefits, rights and obligations herein, the successors and assigns of any Secured Party.

“Subsidiary” or “Subsidiaries” of the Company shall mean any entity whose equity interests are owned entirely by the Company.

“Transaction Agreements” shall mean this Agreement, the Paseco Notes, the RS Bio Notes and all ancillary documents referred to in those agreements, and each of those agreements as may be amended.

“Uniform Commercial Code” shall mean the Uniform Commercial Code as in effect in the State of Delaware from time to time; provided, however, that in the event that, by reason of mandatory provisions of law, any or all of the attachment, perfection, priority, or remedies with respect to the Secured Party’ lien on any Collateral is governed by the Uniform Commercial Code as enacted and in effect in a jurisdiction other than the State of Delaware, the term “Uniform Commercial Code” shall mean the Uniform Commercial Code as enacted and in effect in such other jurisdiction solely for purposes of the provisions thereof relating to such attachment, perfection, priority, or remedies.

Section 2. Representations and Warranties of the Company. The Company hereby represents, warrants, and covenants that: (a) the Company owns or has good and marketable title to the Collateral and no other person or organization can make any claim of ownership of any kind on the Collateral; (b) the Company has the full power, authority and legal right to grant the security interest in the Collateral; (c) the Collateral is free from any and all claims, encumbrances, rights of setoff or any other security interest or lien of any kind except for the security interest in favor of the Secured Party created by this Security Agreement and (d) this Security Agreement creates in favor of the Secured Party a valid security interest in the Collateral, securing payment of the Secured Obligations, and such security interest is first priority.

Section 3. Collateral. As collateral security for the prompt payment in full when due (whether at stated maturity, by acceleration or otherwise) of the Secured Obligations, the Company hereby acknowledges, agrees and confirms that (i) the Secured Parties shall continue to have a security interest in and lien upon and, (ii) to the extent not otherwise previously granted to the Secured Parties, Company hereby pledges, grants, assigns, hypothecates and transfers to the Secured Parties as hereinafter provided, a first priority security interest in and lien upon all of the Company’s wholly-owned assets, whether now existing or hereafter from time to time arising or acquired, and including those set forth on Annex 1 (all of the foregoing being collectively referred to herein as “Collateral”).

Section 4. Further Assurances; Remedies. In furtherance of the grant of the pledge and security interest pursuant to Section 3 hereof, the Company hereby agrees with the Secured Parties as follows:

4.01 Delivery and Other Perfection. The Company shall:

	a.	give, execute, deliver, file and record any financing statement, notice, instrument, document, agreement or other papers that may be necessary or desirable (in the reasonable judgment of the Secured Parties) to create, preserve, maintain, perfect or validate any security interest previously granted or granted pursuant hereto or to enable the Secured Party to exercise and enforce its rights hereunder with respect to such security interest, including, without limitation, upon the occurrence and continuance of an Event of Default, causing any or all of the Collateral to be transferred of record into the name of the Secured Party or its nominee;

	b.	keep accurate books and records relating to the Collateral; and

	c.	permit representatives of the Secured Parties, upon reasonable notice, at any time during normal business hours to inspect and make abstracts from its books and records pertaining to the Collateral, and permit representatives of the Secured Parties to be present at the Company’s place of business to receive copies of all communications and remittances relating to the Collateral, and forward copies of any notices or communications by the Company with respect to the Collateral, all in such manner as the Secured Parties may reasonably require.

4.02 Other Financing Statements and Liens. Without the prior written consent of the Secured Parties, the Company shall not file or suffer to be on file, or authorize or permit to be filed or to be on file, in any jurisdiction, any financing statement or like instrument with respect to the Collateral in which the Secured Parties are not named as the only secured parties.

4.03 Events of Default, etc. Upon the occurrence and during the continuation of an Event of Default, the Secured Parties may exercise any or all of the following rights and remedies:

	a.	require the Company to (and, upon such request, the Company shall) assemble and make available to the Secured Parties the Collateral and all books and records relating thereto at such place or places, reasonably requested by the Secured Parties, whether at the Company’s premises or elsewhere;

	b.	the Secured Parties may make any reasonable compromise or settlement deemed desirable with respect to any of the Collateral and may extend the time of payment, arrange for payment in installments, or otherwise modify the terms of, any of the Collateral;

	c.	the Secured Parties shall have all of the rights and remedies with respect to the Collateral of a secured party under the Uniform Commercial Code (whether or not said Code is in effect in the jurisdiction where the rights and remedies are asserted) and such additional rights and remedies to which a secured party is entitled under the laws in effect in any jurisdiction where any rights and remedies hereunder may be asserted, including, without limitation, the right, to the maximum extent permitted by law, to exercise all voting, consensual and other powers of ownership pertaining to the Collateral as if the Secured Parties were the only and absolute owner thereof (and the Company agrees to take all such action as may be appropriate to give effect to such right);

	d.	the Secured Parties in their discretion may, in its name or in the name of the Company or otherwise, demand, sue for, collect or receive any money or property at any time payable or receivable on account of or in exchange for any of the Collateral, but shall be under no obligation to do so; and

	e.	the Secured Parties may, upon ten (10) days’ prior written notice to the Company of the time and place, with respect to the Collateral or any part thereof which shall then be or shall thereafter come into the possession, custody or control of the Secured Parties, or any of its respective agents, sell, lease, assign or otherwise dispose of all or any of such Collateral, at such place or places as the Secured Parties deem best, and for cash or on credit or for future delivery (without thereby assuming any credit risk), at public or private sale, without demand of performance or notice of intention to effect any such disposition or of time or place thereof (except such notice as is required above or by applicable statute and cannot be waived) and the Secured Parties or anyone else may be the purchaser, lessee, assignee or recipient of any or all of the Collateral so disposed of at any public sale (or, to the extent permitted by law, at any private sale), and thereafter hold the same absolutely, free from any claim or right of whatsoever kind, including any right or equity of redemption (statutory or otherwise), of the Company, any such demand, notice or right and equity being hereby expressly waived and released. The Secured Parties may, without notice or publication, adjourn any public or private sale or cause the same to be adjourned from time to time by announcement at the time and place fixed for the sale, and such sale may be made at any time or place to which the same may be so adjourned.

The proceeds of each collection, sale or other disposition under this Section 4.03, shall be applied in accordance with Section 4.06 hereof.

4.04 Deficiency. If the proceeds of sale, collection or other realization of or upon the Collateral pursuant to Section 4.03 hereof are insufficient to cover the costs and expenses of such realization and the payment in full of the Secured Obligations, the Company shall remain liable for any deficiency.

4.05 Removals, etc. Without at least thirty (30) days’ prior written notice to the Secured Parties or unless otherwise required by law, the Company shall not (i) maintain any of its books or records with respect to the Collateral at any office or maintain its chief executive office or its principal place of business at any place, or permit any Collateral to be located anywhere other than 0000 Xxxxxxx Xxxx X, Xxxxx 000, Xxx Xxxxxxx, XX 00000; or (ii) change its corporate name, or the name under which it does business, from the name shown on the signature page hereto.

4.06 Application of Proceeds. Except as otherwise herein expressly provided, the proceeds of any collection, sale or other realization of all or any part of the Collateral pursuant hereto, and any other cash at the time held by the Secured Parties under this Section 4, shall be applied by the Secured Parties:

First, to the payment of the costs and expenses of such collection, sale or other realization, including reasonable out-of-pocket costs and expenses of the Secured Parties and the fees and expenses of its agents and counsel, and all expenses, and advances made or incurred by the Secured Parties in connection therewith;

Next, to the payment in full of the Secured Obligations in each case equally and ratably in accordance with the respective amounts thereof then due and owing to the Secured Parties; and

Finally, to the payment to the Company, or its successors or assigns, or as a court of competent jurisdiction may direct, of any surplus then remaining.

As used in this Section 4, “proceeds” of Collateral shall mean cash, securities and other property realized in respect of, and distributions in kind of, Collateral, including any thereof received under any reorganization, liquidation or adjustment of debt of the Company or any issuer of or obligor on any of the Collateral.

4.07 Attorney-in-Fact. Without limiting any rights or powers granted by this Agreement to the Secured Parties while no Event of Default has occurred and is continuing, upon the occurrence and during the continuance of any Event of Default, the Secured Parties is hereby appointed the attorney-in-fact of the Company for the purpose of carrying out the provisions of this Section 4 and taking any action and executing any instruments which the Secured Parties may deem necessary or advisable to accomplish the purposes hereof, which appointment as attorney-in-fact is irrevocable and coupled with an interest. Without limiting the generality of the foregoing, so long as the Secured Parties shall be entitled under this Section 4 to make collections in respect of the Collateral, the Secured Parties shall have the right and power to receive, endorse and collect all checks made payable to the order of the Company representing any dividend, payment, or other distribution in respect of the Collateral or any part thereof and to give full discharge for the same.

4.08 Perfection. Prior to or concurrently with the execution and delivery of this Agreement, the Company shall file such financing statements and other documents in such offices as may be necessary (including any such offices as the Secured Parties may request) to perfect or maintain the security interests granted by Section 3 of this Agreement; and without limiting the Company’s obligations with respect to perfection of the security interests, the Company hereby authorizes the Secured Parties to file all such financing statements and other documents (and ratifies any previously filed financing statements and other documents filed by the Secured Parties).

4.09 Termination. When all Secured Obligations shall have been paid in full under the Note, this Agreement shall terminate, and the Secured Parties shall forthwith cause to be assigned, transferred and delivered, against receipt but without any recourse, warranty or representation whatsoever, any remaining Collateral and money received in respect thereof, to or on the order of the Company. The Secured Parties shall also execute and deliver to the Company upon such termination such Uniform Commercial Code termination statements and such other documentation as shall be reasonably requested by the Company, at the Company’s expense, to effect the termination and release of the liens on the Collateral.

4.10 Expenses. The Company agrees to pay to the Secured Parties all out-of-pocket expenses (including reasonable expenses for legal services of every kind) of, or incident to, the enforcement of any of the provisions of this Section 4, or performance by the Secured Parties of any obligations of the Company in respect of the Collateral which the Company has failed or refused to perform upon reasonable notice, or any actual or attempted sale, or any exchange, enforcement, collection, compromise or settlement in respect of any of the Collateral, and for the care of the Collateral and defending or asserting rights and claims of the Secured Parties in respect thereof, by litigation or otherwise, including expenses of insurance, and all such expenses shall be Secured Obligations to the Secured Parties secured under Section 3 hereof.

4.11 Further Assurances. The Company agrees that, from time to time upon the written request of the Secured Parties, the Company will execute and deliver such further documents and do such other acts and things as the Secured Parties may reasonably request in order fully to effect the purposes of this Agreement.

Section 5. Miscellaneous.

5.01 No Waiver. No failure on the part of the Secured Parties or any of its agents to exercise, and no course of dealing with respect to, and no delay in exercising, any right, power or remedy hereunder shall operate as a waiver thereof; nor shall any single or partial exercise by the Secured Parties or any of its agents of any right, power or remedy hereunder preclude any other or further exercise thereof or the exercise of any other right, power or remedy. The remedies herein are cumulative and are not exclusive of any remedies provided by law.

5.02 Governing Law. This Agreement shall be governed by, and construed in accordance with, the law of the State of Delaware.

Notices. All notices, demands, requests, consents, approvals, and other communications required or permitted hereunder shall be in writing and, unless otherwise specified herein, shall be (a) personally served, (b) delivered by reputable international courier service with charges prepaid, or (d) transmitted by hand delivery, telegram, or email (upon confirmation of receipt), addressed as set forth below or to such other address as such party shall have specified most recently by written notice given in accordance herewith. Any notice or other communication required or permitted to be given hereunder shall be deemed effective (i) upon hand delivery or delivery by email (upon confirmation of receipt), or (ii) on the second business day following the date of mailing by reputable international courier service. The addresses for such communications shall be for (i) the Company at 0000 XX 0xx Xxxxxx, #00 Xxxxx, XX 00000, Telephone: (000) 000-0000, Email: xxxxxx@xxxxxxxxxxx.xxx with a copy to xxxxxxx.xxxxxx@xxxxxxx.xxx, (ii) Paseco at Vedbaek Xxxxxxxxx 000, 0000 Xxxxxxx, Xxxxxxx and (iii) RS Bio at Xxxxxxxxxxxxxx 00, 0000 Xxxxxxxx, Xxxxxxx, Email: xx@xxxxxxx.xx with a copy to xxxxxxxx@xxxxxxx.xxx. Any party hereto may from time to time change its address or facsimile number for notices under this Section by written notice to the other parties.

5.03 Waivers, etc. The terms of this Agreement may be waived, altered or amended only by an instrument in writing duly executed by the Company and the Secured Parties. Any such amendment or waiver shall be binding upon the Secured Parties and the Company.

5.04 Successors and Assigns. This Agreement shall be binding upon and inure to the benefit of the respective successors and assigns of the Company and the Secured Parties (provided, however, that the Company shall not assign or transfer its rights hereunder without the prior written consent of the Secured Parties.

5.05 Counterparts; Execution; Additional Secured Party. This Agreement may be executed in any number of counterparts, all of which together shall constitute one and the same instrument and any of the parties hereto may execute this Agreement by signing any such counterpart. In the event that any signature is delivered by facsimile transmission or by e-mail delivery of a “.pdf” format data file, such signature shall create a valid and binding obligation of the party executing (or on whose behalf such signature is executed) with the same force and effect as if such facsimile or “.pdf” signature page was an original thereof. In the event additional Secured Parties become holders of the Paseco Notes or RS Bio Notes, such Secured Party will become a party to this Agreement by signing a counterpart to this Agreement in a form reasonably acceptable to the Secured Parties, all of which together shall be considered one and the same instrument. The Company shall provide a copy of each counterpart to this Agreement executed by a Secured Party to the Secured Parties.

5.06 Severability. If any provision hereof is invalid and unenforceable in any jurisdiction, then, to the fullest extent permitted by law, (i) the other provisions hereof shall remain in full force and effect in such jurisdiction and shall be liberally construed in favor of the Secured Parties in order to carry out the intentions of the parties hereto as nearly as may be possible and (ii) the invalidity or unenforceability of any provision hereof in any jurisdiction shall not affect the validity or enforceability of such provision in any other jurisdiction.

5.07 Entire Agreement. This Agreement and the other Transaction Agreements contains the entire agreement and understanding by and between the parties hereto with respect to the subject matter hereof and their resulting obligations to each other, as herein described; and it amends, restates and supersedes all prior agreements and understandings between the parties to this Agreement relating to the subject matter hereof. No change or modification of this Agreement shall be valid or binding unless the same is in writing and signed by the party intended to be so bound. No waiver of any provision of this Agreement shall be valid unless the same is in writing and signed by the party against whom such waiver is sought to be enforced. Moreover, no valid waiver of any provision of this Agreement, at any time, shall be deemed to be a waiver of any other provision of this Agreement at such time, or shall be deemed to be a valid waiver of such provision at any other time.

[The remainder of this page intentionally left blank.]

IN WITNESS WHEREOF, the parties hereto have caused this Security Agreement to be duly executed as of the day and year first above written.

The “Company”:		The “Secured Parties”:

RENOVARO BIOSCIENCES INC.		PASECO APS

By:	/s/ Xxxxx Xxxxx	By:	/s/ Xxx Xxxxxxxxxx
Name:	Xxxxx Xxxxx	Name:	Xxx Xxxxxxxxxx
Title:	Chief Financial Officer	Title:	Chief Executive Officer

		RS BIO APS

		By:	/s/ Xxxx Xxxxxxx
		Name:	Xxxx Xxxxxxx
		Title:	Chief Executive Officer

ANNEX 1

●

All fixed assets located at:

o 0000 Xxxxxxx Xxxx X, Xxxxx 000, Xxx Xxxxxxx, XX 00000

	●	The Intellectual property set forth below:

	●	ALLOGENEIC T-CELL-BASED HIV VACCINE TO INDUCE CELLULAR AND HUMORAL IMMUNITY

Inventor(s): Xxxxxx Xxxxxxxx

Assignee: Renovaro Biopharma Inc.

Country	Appl. No.	Filing Date	Pub. No./ Pub. Date	Patent No. / Issue Date	Status
US	16/904,319	6/17/2020	US2021/0030795 02/04/2021		Pending
AU	2020294700	6/17/2020			Pending
BR	BR1120210252860	6/17/2020			Pending
CA	3143599	6/17/2020			Pending
CN	202080056674.7	6/17/2020			Pending
EP	20826762.5	6/17/2020	EP3982981 04/20/2022		Pending
HK	62022062396.6	6/17/2020			Pending
IL	288945	1/17/2020			Pending
IN	202217000341	6/17/2020			Pending
JP	2021-574918	6/17/2020			Pending
KR	00-0000-0000000	1/11/2022			Pending
MX	MX/a/2021/015643	6/17/2020			Pending
NZ	784083	6/17/2020			Pending
ZA	2021/10224	6/17/2020			Pending
SG	11202113941W	12/15/2021			Pending

METHODS AND COMPOSITIONS USING RECOMBINANT DENDRITIC CELLS FOR CANCER THERAPY

Inventor(s): Xxxxxx Xxxxxxxx

Assignee: Renovaro Biopharma Inc.

Country	Appl. No.	Filing Date	Pub. No./ Pub. Date	Patent No./ Issue Date	Status
US	16/511,413	7/15/2019		11,413,338 08/16/2022	Granted
AE	P6000067/21	7/15/2019			Pending
AU	2019306504	7/15/2019			Pending
BH	20210012	7/15/2019			Pending
BR	BR112021000620 6	7/15/2019			Pending
CA	3106403	7/15/2019			Pending
CN	201980051688.7	7/15/2019			Pending
EA	202190267	7/15/2019			Pending
EP	19837951.3	7/15/2019	EP3820486 05/19/2021		Pending
GE	201915555	7/15/2019			Pending
HK-CN	62021039668.0	9/28/2021			Pending
HK-EP	62021042617.2	11/17/2021			Pending
IL	280145	7/15/2019			Pending
IN	202117004635	7/15/2019			Pending
JP	2021-502920	7/15/2019			Pending
KR	10-2021-700-3120	7/15/2019			Pending
MX	MX/a/2021/000421	7/15/2019			Pending
MY	PI2021000186	7/5/2019			Pending
NZ	000	7/15/2019			Pending
QA	QA/202101/00027	7/15/2019			Pending
SA	521421034	7/15/2019			Pending
SG	11202100315T	7/15/2019			Pending
UA	a202100559	7/15/2019			Pending
VN	0-0000-00000	7/15/2019			Pending
ZA	2021/00234	1/13/2021		2021/00234 07/27/2022	Granted

Your ref.	Applicant	Country	Appl. No.	Pat. No.	Year
Protocol for generating dendritic	DanDrit Biotech A/S	Canada	2640836	2640836	18
PROTOCOL FOR GENER. DENDRITIC CELLS	DanDrit Biotech A/S	New Zealand	569343	569343	18
PROTOCOL FOR GEN. DENDRITIC CELLS	DanDrit Biotech A/S	China	200680045697.8	200680045697.8	18
PROTOCOL FOR GEN. DENDRITIC CELLS	DanDrit Biotech A/S	Australia	2013203315	2013203315	18
PROTOCOL FOR GENER. DENDRITIC CELLS	DanDrit Biotech A/S	Switzerland	06818153.6	1971680	18
PROTOCOL FOR GENER. DENDRITIC CELLS	DanDrit Biotech A/S	Germany	06818153.6	602006027671.0	18
PROTOCOL FOR GENER. DENDRITIC CELLS	DanDrit Biotech A/S	Denmark	06818153.6	1971680	18
PROTOCOL FOR GENER. DENDRITIC CELLS	DanDrit Biotech A/S	Spain	06818153.6	1971680	18
PROTOCOL FOR GENER. DENDRITIC CELLS	DanDrit Biotech A/S	France	06818153.6	1971680	18
PROTOCOL FOR GENER. DENDRITIC CELLS	DanDrit Biotech A/S	Italy	06818153.6	1971680	18
PROTOCOL FOR GEN. DENDRITIC CELLS	DanDrit Biotech A/S	Israel	191782	191782	19-

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AMENDED AND RESTATED SECURITY AGREEMENT

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