June 29, 2010 Patheon.com

[PATHEON] Exhibit 10.31

0000 Xxxxxxxxxxx Xxxx, Xxxxx 000

Xxxxxxxxxxx, Xxxxxxx X0X 0X0

xxx.xxxxxxx.xxx

June 29, 2010 Xxxxxxx.xxx

Xx. Xxxx X. Xxxxxxxxx

Xxxxxxxxxxx XX

0000 Xxx

Xxxxxxxxxxx

Re: First Amendment to Employment Agreement

Dear Doaa:

I am writing to confirm our agreement to amend the language of your May 6, 2008 Employment Agreement with Patheon International AG, as successor entity to Patheon International GmbH (the “Employment Agreement”) as follows:

8. International Relocation Allowance

The Company shall continue to pay you the international relocation allowance amount set forth in your Employment Agreement for so long as you are working for Patheon in Switzerland.

Very truly yours,
/s/ Xxxxxx X. Xxxxxxx
Patheon International AG
By:		Xxxxxx X. Xxxxxxx
Title:		Authorized Signatory