EXHIBIT 1 --------- JOINT FILING AGREEMENT PURSUANT TO RULE 13d-1(k)(1) The undersigned acknowledge and agree that the foregoing statement on Schedule 13G is filed on behalf of each of the undersigned and that all subsequent amendments to this...
CUSIP NO. 000000000 Schedule 13G Page 21 of 26
EXHIBIT 1
---------
JOINT FILING AGREEMENT PURSUANT TO RULE 13d-1(k)(1)
The undersigned acknowledge and agree that the foregoing
statement on Schedule 13G is filed on behalf of each of the undersigned and that
all subsequent amendments to this statement on Schedule 13G shall be filed on
behalf of each of the undersigned without the necessity of filing additional
joint filing statements. The undersigned acknowledge that each shall be
responsible for the timely filing of such amendments, and for the completeness
and accuracy of the information concerning him, her or it contained herein, but
shall not be responsible for the completeness and accuracy of the information
concerning the other entities or persons, except to the extent that he, she or
it knows or has reason to believe that such information is inaccurate.
Dated as of February 17, 2004
PERSEUS-XXXXX BIOPHARMACEUTICAL FUND, L.P.
By: Perseus-Xxxxx Partners, LLC
General Partner
By: SFM Participation, L.P.
Managing Member
By: SFM AH LLC
General Partner
By: Xxxxx Fund Management LLC
Managing Member
By: /s/ Xxxxx X. Xxxxxxxxx
--------------------------------------
Name: Xxxxx X. Xxxxxxxxx
Title: Assistant General Counsel
CUSIP NO. 000000000 Schedule 13G Page 22 of 26
PERSEUS-XXXXX PARTNERS, LLC
By: SFM Participation, L.P.
Managing Member
By: SFM AH LLC
General Partner
By: Xxxxx Fund Management LLC
Managing Member
By: /s/ Xxxxx X. Xxxxxxxxx
--------------------------------------
Name: Xxxxx X. Xxxxxxxxx
Title: Assistant General Counsel
PERSEUS BIOTECH FUND PARTNERS, LLC
By: Perseuspur EC, L.L.C.
Managing Member
By: Perseuspur, LLC
Member
By: /s/ Xxxx Xxxxxxx
---------------------------------------
Name: Xxxx Xxxxxxx
Title: Secretary and Treasurer
SFM PARTICIPATION, L.P.
By: SFM AH LLC
General Partner
By: Xxxxx Fund Management LLC
Managing Member
By: /s/ Xxxxx X. Xxxxxxxxx
--------------------------------------
Name: Xxxxx X. Xxxxxxxxx
Title: Assistant General Counsel
CUSIP NO. 000000000 Schedule 13G Page 23 of 26
SFM AH LLC
By: Xxxxx Fund Management LLC
Managing Member
By: /s/ Xxxxx X. Xxxxxxxxx
--------------------------------------
Name: Xxxxx X. Xxxxxxxxx
Title: Assistant General Counsel
PERSEUS EC, L.L.C.
By: Perseuspur, LLC
Member
By: /s/ Xxxx Xxxxxxx
---------------------------------------
Name: Xxxx Xxxxxxx
Title: Secretary and Treasurer
PERSEUSPUR, LLC
By: /s/ Xxxx Xxxxxxx
---------------------------------------
Name: Xxxx Xxxxxxx
Title: Secretary and Treasurer
XX. XXXXX X. XXXXX
By: /s/ Xxxx Xxxxxxx
---------------------------------------
Name: Xxxx Xxxxxxx
Title: Attorney-in-Fact (1)
MR. XXXXXX XXXXX
By: /s/ Xxxxx X. Xxxxxxxxx
----------------------------------------
Name: Xxxxx X. Xxxxxxxxx
Title: Attorney-in-Fact (2)
CUSIP NO. 000000000 Schedule 13G Page 24 of 26
XXXXX FUND MANAGEMENT LLC
By: /s/ Xxxxx X. Xxxxxxxxx
--------------------------------------
Name: Xxxxx X. Xxxxxxxxx
Title: Assistant General Counsel
------------------------
(1) A Power of Attorney, dated April 9, 2003, appointing Xxxx Xxxxxxx to act on
behalf of Xxxxx Xxxxx has been filed with the Securities and Exchange
Commission.
(2) A Power of Attorney, dated October 30, 2002, appointing each of Xxxxxxx X.
Xxxxx, Xxxxx Xxxxxxxxx, Xxxx X. Xxxxx, Xxxxxxx Xxxxxxxx, Xxxxxxx X.
Xxxxxxx, Xx. and Xxxxxx Xxxxx to act on behalf of Xxxxxx Xxxxx has been
filed with the Securities and Exchange Commission.
