Iowa State University Research Park Corporation

Exhibit 10.62.1

Iowa State University Research Park Corporation

0000 Xxxxx Xxxx Xxxxx, Xxxxx 0000

Xxxx, Xxxx 00000-0000

Memorandum of Agreement

DATE: July 9, 2015

TO: Xxxx Xxxxxxx, VP Finance

NewLink Genetics Corporation

0000 X. Xxxx Xxxxx, Xxxxx 0000

Xxxx, XX 00000

FROM: Xxxxxx X. Xxxxxx, President

RE: ADDENDUM TO THE LEASE BETWEEN ISU RESEARCH PARK CORPORATION AND NEWLINK GENETICS CORPORATION DATED MARCH 1, 2010.

The following information constitutes changes to the Lease Agreement between ISU Research Park Corporation (Landlord) and NewLink Genetics Corporation (Tenant). Upon signatures of appropriate representatives of Landlord and Tenant affixed to this Memorandum, this Memorandum becomes a part of that Lease Agreement dated March 1, 2010.

Tenant has requested and Landlord agrees to lease Suite 2130 (±2,070 rentable square feet), Building #2 at 0000 Xxxxx Xxxx Xxxxx, in the following manner:

Sq. Ft. Sq. Ft. Monthly Monthly Annual Annual

Base Operating Base Operating Base Operating

Term Rents Rents Rents Rents Rents Rents

8/1/2015-

1/31/2018 $10.50 Actual $1,811.25 Actual $21,735.00 Actual

Tenant leases the space as is. Any modifications will be at the Tenant’s sole expense. Tenant is responsible for all utility costs and operations. Subject to the terms of this Memorandum, Tenant agrees that all terms and conditions of the March 1, 2010 Lease and those described in this Memorandum shall remain in force.

Exhibit 10.62.1

NewLink Genetics Corporation

Page Two

July 9, 2015

Please sign and return both originals to my office by July 15, 2015 if you concur with the above terms. We will then send a fully executed copy for your records.

AGREED

FOR FOR

NewLink Genetics Corporation ISU Research Park Corporation

/s/ Xxxx Xxxxxxx                    /s/ Xxxxxx Xxxxxx

VP Finance                        Director

Title Title

July 9, 2015                        July 13, 2015

Date Date

Word/ISURP/Addendums/Adden NewLink 2130 Aug15.doc