License Agreement By and Among Axcan Holdings Inc., Axcan Lone Star Inc. and Mpex Pharmaceuticals, Inc. April 11, 2011
Exhibit 2.4
By and Among
Axcan Holdings Inc.,
Axcan Lone Star Inc.
and
Mpex Pharmaceuticals, Inc.
April 11, 2011
This License Agreement (this “Agreement”) is entered into and made effective as of
the 11th day of April, 2011 (the “Effective Date”) by and among Mpex
Pharmaceuticals, Inc., a Delaware corporation having its principal place of business at 00000
Xxxxxxxx Xxxxxx Xxxx, Xxx Xxxxx, XX 00000 (the “Company”), Axcan Holdings Inc., a Delaware
corporation having offices at 000 Xxxxxxxx Xxxxxxxxx Xxxxxxxxx, Xxxxxxxxxxx, Xxx Xxxxxx 00000
(“Acquiror”), and Axcan Lone Star Inc., a Delaware corporation and indirect wholly owned subsidiary
of Acquiror (“Sub”, and collectively with Acquiror, “Axcan”). The Company and Axcan are each
referred to herein by name or as a “Party” or, collectively, as “Parties.”
RECITALS
Whereas, the Company possesses proprietary technology and know-how related to the
Product (as defined below);
Whereas, as of the Effective Date, the Company, Acquiror and Sub have entered into
that certain Development Agreement (the “Development Agreement”) with respect to the development
and pre-commercialization activities with respect to the Product;
Whereas, as of the Effective Date, the Company, Acquiror, Sub and the
Securityholders’ Representative Committee have entered into that certain Agreement and Plan of
Merger (the “Merger Agreement”), pursuant to which Acquiror has the right to acquire all
outstanding shares of the Company on the terms and conditions set forth in the Merger Agreement,
and the Company, Acquiror and Sub have entered into that certain Option Agreement (the “Option
Agreement”), pursuant to which Axcan has an option to terminate the Merger Agreement in accordance
with the terms and conditions set forth in the Option Agreement; and
Whereas, Axcan wishes to have, and the Company wishes to grant to Axcan, a
non-exclusive license for Axcan to develop the Product during the term of the Option Agreement and
the Merger Agreement.
Now, therefore, in consideration of the premises and mutual covenants herein
contained, and for other good and valuable consideration, the receipt and sufficiency of which are
hereby acknowledged, the Parties hereto agree as follows:
ARTICLE 1
DEFINITIONS
As used in this Agreement, the following terms shall have the meanings set forth in this ARTICLE 1,
and any other capitalized terms that are not otherwise defined herein shall have the respective
meanings given to them in the Merger Agreement:
1.1 “AAA” has the meaning assigned to such term in Section 5.2.3.
1.2 “Acquiror” has the meaning assigned to such term in the Preamble.
1.3 “Aeroquin™ IP” has the meaning assigned to such term in the Option Agreement.
1.4 “Affiliate” means any Person, whether de jure or de facto, which directly or indirectly
through one (1) or more intermediaries controls, is controlled by or is under common control with a
Party. A Person shall be deemed to “control” another Person if it (a) owns, directly or
indirectly, beneficially or legally, at least fifty percent (50%) of the outstanding voting
securities or capital stock (or such lesser percentage which is the maximum allowed to be owned by
a Person in a particular jurisdiction) of such other Person, or has other comparable ownership
interest with respect to any Person other than a corporation; or (b) has the power, whether
pursuant to contract, ownership of securities or otherwise, to direct the management and policies
of the Person. For the purposes of clarity, the Company is not an Affiliate of Axcan or any of its
subsidiaries at any time prior to the closing of the Merger in accordance with the terms of the
Merger Agreement, if any.
1.5 “Agreement” has the meaning assigned to such term in the Preamble.
1.6 “Arbitration Request” has the meaning assigned to such term in Section 5.2.
1.7 “Axcan” has the meaning assigned to such term in the Preamble.
1.8 “Company” has the meaning assigned to such term in the Preamble.
1.9 “Control,” “Controls,” “Controlled” or “Controlling” means possession of the ability to
grant the licenses or sublicenses without violating the terms of any agreement or other arrangement
with any Third Party.
1.10 “Development Agreement” has the meaning assigned to such term in the Recitals.
1.11 “Development IP” means any and all intellectual property (including Patents, Information
and copyrights) arising after the Effective Date and resulting directly or indirectly from the
Company’s performance of the Development Plan. For clarity, the phrase “the Company’s performance”
in the preceding sentence refers to both (a) the performance of the Company between the Effective
Date and the date of assumption of the Development Agreement by Spinco pursuant to Section 2.1 of
the Development Agreement and (b) the performance of Spinco between the date of assumption of the
Development Agreement by Spinco pursuant to Section 2.1 of the Development Agreement and the end of
the “Term” of the Development Agreement.
1.12 “Effective Date” has the meaning assigned to such term in the Preamble.
1.13 “Executive Officers” has the meaning assigned to such term in the Development Agreement.
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1.14 “Information” means all tangible and intangible (a) information, techniques, technology,
practices, trade secrets, inventions (whether patentable or not), methods, knowledge, know-how,
skill, experience, data, results (including pharmacological, biological, chemical, biochemical,
toxicological and clinical test data and results), analytical and quality control data, results or
descriptions, software and algorithms and (b) compositions of matter, cells, cell lines, assays,
animal models and physical, biological or chemical material. As used in the preceding sentence,
“clinical test data” shall be deemed to include all information related to the clinical or
pre-clinical testing, including patient report forms, investigators’ reports, biostatistical,
pharmaco-economic and other related analyses, regulatory filings and communications, and the like.
1.15 “Merger Agreement” has the meaning assigned to such term in the Recitals.
1.16 “Option Agreement” has the meaning assigned to such term in the Recitals.
1.17 “Party” or “Parties” has the meaning assigned to such term in the Preamble.
1.18 “Patent” has the meaning assigned to such term in the Development Agreement.
1.19 “Product” means the pharmaceutical product currently identified as Aeroquin™, consisting
of the levofloxacin compound that is formulated for delivery through the device currently
identified as the PARI eFlow® Device.
1.20 “Sub” has the meaning assigned to such term in the Preamble.
1.21 “Term” has the meaning assigned to such term in Section 3.1.
1.22 “Third Party” means any entity other than the Company, Acquiror, Sub or an Affiliate of
the Company, Acquiror or Sub.
1.23 “United States” or “U.S.” means the United States of America.
ARTICLE 2
DEVELOPMENT LICENSE
2.1 Development License. The Company hereby grants Axcan a non-exclusive, worldwide,
fully paid, royalty-free (except for payments, earn-out payments and milestone payments required
under the Development Agreement, Option Agreement and Merger Agreement) license, under the
Aeroquin™ IP and Development IP, to Develop (as defined in the Development Agreement) and have
Developed the Product. For purposes of clarity, in no event shall Axcan be deemed to have a
license, under the Aeroquin™ IP or Development IP, to Commercialize (as defined in the Development
Agreement) or otherwise sell the Product under this Agreement or the Development Agreement.
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ARTICLE 3
TERM AND TERMINATION
3.1 Term; Expiration. This Agreement shall become effective as of the Effective Date
and, unless earlier terminated pursuant to the other provisions of this ARTICLE 3, shall expire
upon the earliest of (a) termination of the Development Agreement, (b) the Effective Time and
(c) delivery of a Termination Notice (as defined in the Option Agreement) as contemplated by
Section 2.3.2 of the Option Agreement (the “Term”).
3.2 Termination by the Parties. Notwithstanding Section 3.1 above, either Party may,
without prejudice to any other remedies available to it at law or in equity, terminate this
Agreement in the event the other Party shall have materially breached any of its representations or
warranties, or shall have materially breached or defaulted in the performance of any of its
material obligations, hereunder; provided, however, that, if such breach or default
is curable, then the breaching or defaulting Party shall have thirty (30) calendar days after the
other Party provides it with written notice of breach or default, such notice describing with
particularity and in detail the alleged material breach or material default, to cure such breach or
default. Any such termination of this Agreement under this Section 3.2 shall become effective upon
notice of the breach or default, or, if applicable, at the end of such thirty (30) calendar day
period, unless such breach or default was cured prior to the expiration of such thirty (30)
calendar day period. The right of the Parties to terminate this Agreement as provided in this
Section 3.2 shall not be affected in any way by a Party’s waiver or failure to take action with
respect to any previous default.
3.3 Accrued Rights; Surviving Provisions of the Agreement.
(a) In the event of the expiration or any termination of this Agreement, notwithstanding
anything contained herein to the contrary, all rights granted to Axcan shall terminate;
provided, however, that any rights granted to Axcan pursuant to the applicable
definitions in ARTICLE 1 and/or the provisions in ARTICLE 5 shall survive the termination or
expiration of this Agreement for any reason in accordance with Section 3.3(c).
(b) Termination, relinquishment or expiration of this Agreement for any reason shall be
without prejudice to any rights that shall have accrued to the benefit of any Party prior to such
termination, relinquishment or expiration, including any and all damages arising from any breach or
default hereunder. Such termination, relinquishment or expiration shall not relieve any Party from
obligations which are expressly indicated to survive termination of this Agreement.
(c) Any applicable definitions in ARTICLE 1 and the provisions in ARTICLE 5, shall survive the
termination or expiration of this Agreement for any reason, in accordance with their respective
terms and conditions, and for the duration stated, and where no duration is stated, shall survive
indefinitely.
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ARTICLE 4
REPRESENTATIONS AND WARRANTIES
4.1 Each Party represents and warrants to the other Party as follows:
4.1.1 Such Party is a corporation duly organized, validly existing and in good standing
under the laws of its jurisdiction of organization. Such Party is not in violation of any
of the provisions of its certificate of incorporation or by-laws.
4.1.2 Such Party has all requisite corporate power and authority to enter into this
Agreement and to consummate the transactions contemplated hereby. The execution, delivery
and performance by such Party of this Agreement, and the consummation by such Party of the
transactions contemplated hereby, have been duly and validly authorized by the board of
director of such Party. This Agreement has been duly and validly executed and delivered by
such Party, and constitutes a valid and binding obligation of such Party enforceable against
such Party in accordance with its terms.
4.1.3 The execution and delivery of this Agreement by such Party do not, and neither
the consummation of the transactions contemplated hereby nor compliance by such Party with
any provisions of this Agreement will, conflict with, or result in any violation of, or
default under (with or without notice or lapse of time, or both), or give rise to a right of
termination, cancellation or acceleration of any obligation or loss of any benefit under, or
obligate such Party to make any payment under (i) any provision of its certificate of
incorporation or by-laws, as amended to date, or (ii) any Legal Requirement.
ARTICLE 5
MISCELLANEOUS
5.1 Dispute Resolution. Unless otherwise set forth in this Agreement, in the event of
a dispute arising under this Agreement between the Parties, either Party shall have a right to
refer such dispute to the Executive Officers, and the Executive Officers shall attempt in good
faith to resolve such dispute. If the Parties are unable to resolve a given dispute pursuant to
this Section 5.1 within thirty (30) calendar days of referring such dispute to the Executive
Officers, either Party may have the given dispute settled by binding arbitration pursuant to
Section 5.2.
5.2 Arbitration Request. If a Party intends to begin an arbitration to resolve a
dispute arising under this Agreement, such Party shall provide written notice (the “Arbitration
Request”) to the other Party of such intention and the issues for resolution. From the date of the
Arbitration Request and until such time as the dispute has become finally settled, the running of
the time periods as to which Party must cure a breach of this Agreement becomes suspended as to any
breach that is the subject matter of the dispute.
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5.2.1 Additional Issues. Within twenty (20) Business Days after the receipt of
the Arbitration Request, the other Party may, by written notice, add additional issues for
resolution.
5.2.2 No Arbitration of Patent/Confidentiality Issues. Unless otherwise agreed
by the Parties, disputes relating to Patents or non-disclosure, non-use or maintenance of
Confidential Information shall not be subject to arbitration, and shall be submitted to a
court of competent jurisdiction.
5.2.3 Arbitration Procedure. The Arbitration shall be held in the continental
United States under the rules of the American Arbitration Association (“AAA”). The
arbitration shall be conducted by three (3) arbitrators who are knowledgeable in the subject
matter at issue in the dispute. One (1) arbitrator will be selected by the Company, one (1)
arbitrator will be selected by Axcan, and the third arbitrator will be selected by mutual
agreement of the two (2) arbitrators selected by the Parties. The arbitrators may proceed
to an award, notwithstanding the failure of either Party to participate in the proceedings.
The arbitrators shall, within fifteen (15) calendar days after the conclusion of the
arbitration hearing, issue a written award and statement of decision describing the
essential findings and conclusions on which the award is based, including the calculation of
any damages awarded. The arbitrators shall be authorized to award compensatory damages, but
shall not be authorized to award non-economic damages or punitive, special, consequential,
or any other similar form of damages, or to reform, modify or materially change this
Agreement. The arbitrators also shall be authorized to grant any temporary, preliminary or
permanent equitable remedy or relief the arbitrators deem just and equitable and within the
scope of this Agreement, including an injunction or order for specific performance. The
award of the arbitrators shall be the sole and exclusive remedy of the Parties (except for
those remedies set forth in this Agreement), the Parties hereby expressly agree to waive the
right to appeal from the decisions of the arbitrators, and there shall be no appeal to any
court or other authority (government or private) from the decision of the arbitrators.
Judgment on the award rendered by the arbitrators may be enforced in any court having
competent jurisdiction thereof, subject only to revocation on grounds of fraud or clear bias
on the part of the arbitrators. Notwithstanding anything contained in this Section 5.2 to
the contrary, each Party shall have the right to institute judicial proceedings against the
other Party or anyone acting by, through or under such other Party, in order to enforce the
instituting Party’s rights hereunder through specific performance, injunction or similar
equitable relief.
5.3 Costs. Each Party shall bear its own attorneys’ fees, costs and disbursements
arising out of the arbitration, and shall pay an equal share of the fees and costs of the
arbitrators; provided, however, that the arbitrators shall be authorized to
determine whether a Party is the prevailing Party, and if so, to award to that prevailing Party
reimbursement for its reasonable attorneys’ fees, costs and disbursements (including, for example,
expert witness fees and expenses, photocopy charges and travel expenses).
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5.4 Confidentiality. All proceedings and decisions of the arbitrators shall be deemed
Confidential Information of each of the Parties.
5.5 Governing Law. This Agreement and any dispute arising from the performance or
breach hereof shall be governed by and construed and enforced in accordance with the laws of the
State of Delaware without reference to conflicts of laws principles.
5.6 Assignment. Neither this Agreement nor any of the rights, interests or
obligations under this Agreement may be assigned or delegated, in whole or in part, by operation of
law or otherwise, by any Party without the prior written consent of the other Party, and any such
assignment without such prior written consent shall be null and void. Any change of control,
merger, consolidation or otherwise or sale of substantially all of the assets of a Party shall be
deemed an assignment or delegation of this Agreement. Notwithstanding the foregoing, either Party
may assign this Agreement to any direct or indirect wholly owned subsidiary of such Party without
the prior consent of other Party; provided, however, that such Party shall remain
liable for all of its obligations under this Agreement. Subject to the preceding sentence, this
Agreement shall be binding upon, inure to the benefit of, and be enforceable by, the Parties and
their respective successors and assigns.
5.7 Specific Performance. The Parties acknowledge and agree that monetary damages
would not adequately compensate an injured party for the breach of this Agreement by the other
Party, that this Agreement shall be specifically enforceable and that any breach of this Agreement
shall be the proper subject of a temporary or permanent injunction or restraining order. Further,
each Party hereto waives any claim or defense that there is an adequate remedy at law for such
breach.
5.8 Notices. Any notice or request required or permitted to be given under or in
connection with this Agreement shall be deemed to have been sufficiently given if in writing and
personally delivered or sent by certified mail (return receipt requested), facsimile transmission
(receipt verified) or overnight express courier service (signature required), prepaid, to the Party
for which such notice is intended, at the address set forth for such Party below:
If to the Company, addressed to:
|
Mpex Pharmaceuticals, Inc. 00000 Xxxxxxxx Xxxxxx Xxxx Xxx Xxxxx, XX 00000 Attention: President Facsimile: (000) 000-0000 |
|
with a copy to:
|
DLA Piper LLP (US) 0000 Xxxxxxxxx Xxxxx, Xxxxx 0000 Xxx Xxxxx, XX 00000 Attention: Xxxx X. Xxxxxxxxxx Facsimile: (000) 000-0000 |
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If to Axcan, addressed to:
|
Axcan Holdings Inc. 000 Xxxxxxxx Xxxxxxxxx Xxxxxxxxx Xxxxxxxxxxx, Xxx Xxxxxx 00000 Attention: Xxxxx Xxxxxxx Facsimile: (000) 000-0000 |
|
with a copy to:
|
Axcan Holdings Inc. 000 Xxxxxxxx Xxxxxxxxx Xxxxxxxxx Xxxxxxxxxxx, Xxx Xxxxxx 00000 Attention: Xxxxx Xxxxxxx Facsimile: (000) 000-0000 |
|
with a copy to:
|
Ropes & Xxxx LLP Prudential Tower 000 Xxxxxxxx Xxxxxx Xxxxxx, XX 00000-0000 Attention: Xxxx X. Xxxxxxxxxx Facsimile: (000) 000-0000 |
or to such other address for such Party as it shall have specified by like notice to the other
Party, provided that notices of a change of address shall be effective only upon receipt thereof.
If delivered personally or by facsimile transmission, the date of delivery shall be deemed to be
the date on which such notice or request was given. If sent by overnight express courier service,
the date of delivery shall be deemed to be the next Business Day after such notice or request was
deposited with such service. If sent by certified mail, the date of delivery shall be deemed to be
the third (3rd) Business Day after such notice or request was deposited with the U.S.
Postal Service.
5.9 Waiver. Neither Party may waive or release any of its rights or interests in this
Agreement except in writing. The failure of either Party to assert a right hereunder or to insist
upon compliance with any term or condition of this Agreement shall not constitute a waiver of that
right or excuse a similar subsequent failure to perform any such term or condition. No waiver by
either Party of any condition or term in any one or more instances shall be construed as a
continuing waiver of such condition or term or of another condition or term.
5.10 Severability. If any provision hereof should be held invalid, illegal or
unenforceable in any jurisdiction, the Parties shall negotiate in good faith a valid, legal and
enforceable substitute provision that most nearly reflects the original intent of the Parties, and
all other provisions hereof shall remain in full force and effect in such jurisdiction and shall be
liberally construed in order to carry out the intentions of the Parties hereto as nearly as may be
possible. Such invalidity, illegality or unenforceability shall not affect the validity, legality
or enforceability of such provision in any other jurisdiction.
5.11 Further Assurances. Each of the Parties agrees to use its commercially
reasonable efforts, and to cooperate with the other Party, to take, or cause to be taken, all
actions, and to do, or cause to be done, all things, necessary, appropriate or desirable to
consummate and
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make effective, in the most expeditious manner practicable, the transactions contemplated
hereby, and including to execute and deliver such other instruments and do and perform such other
acts and things as may be necessary or reasonably desirable for effecting completely the
consummation of the transactions contemplated hereby.
5.12 Entire Agreement. This Agreement, together with the Option Agreement, the Merger
Agreement and the Development Agreement, set forth all the covenants, promises, agreements,
warranties, representations, conditions and understandings between the Parties hereto, and
supersede and terminate all prior agreements and understanding between the Parties except for the
Confidentiality Agreement (as defined in Section 5.2.1 of the Option Agreement). There are no
covenants, promises, agreements, warranties, representations, conditions or understandings, either
oral or written, between the Parties other than as set forth herein and therein. No subsequent
alteration, amendment, change or addition to this Agreement shall be binding upon the Parties
hereto unless reduced to writing and signed by the respective authorized officers of the Parties.
5.13 Headings; Interpretation. Headings used herein are for convenience only and
shall not in any way affect the construction of or be taken into consideration in interpreting this
Agreement. Further, in this Agreement: (a) the word “including” shall be deemed to be followed by
the phrase “without limitation” or like expression; (b) the singular shall include the plural and
vice versa; and (c) masculine, feminine and neuter pronouns and expressions shall be
interchangeable.
5.14 Parties in Interest. All of the terms and provisions of this Agreement shall be
binding upon, and shall inure to the benefit of and be enforceable by the Parties hereto and their
respective successors, heirs, administrators and permitted assigns. For the avoidance of doubt, at
the Effective Time, the Surviving Corporation shall assume all of Sub’s obligations, and succeed to
all of Sub’s rights, that survive the termination of this Agreement.
5.15 Construction of Agreement. The terms and provisions of this Agreement represent
the results of negotiations between the Parties and their representatives, each of which has been
represented by counsel of its own choosing, and neither of which has acted under duress or
compulsion, whether legal, economic or otherwise. Accordingly, the terms and provisions of this
Agreement shall be interpreted and construed in accordance with their usual and customary meanings,
and each of the Parties hereto hereby waives the application in connection with the interpretation
and construction of this Agreement of any rule of law to the effect that ambiguous or conflicting
terms or provisions contained in this Agreement shall be interpreted or construed against the Party
whose attorney prepared the executed draft or any earlier draft of this Agreement.
5.16 Counterparts. This Agreement may be signed in counterparts, each and every one
of which shall be deemed an original, notwithstanding variations in format or file designation
which may result from the electronic transmission, storage and printing of copies of this Agreement
from separate computers or printers. Facsimile signatures and signatures transmitted via PDF shall
be treated as original signatures.
* — * — * — *
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IN WITNESS WHEREOF, the Parties have caused this License Agreement to be executed by their
duly authorized representatives as of the Effective Date.
| MPEX PHARMACEUTICALS, INC. | ||||
By:
|
/s/ Xxxxxx Xxxxxxx | |||
Name:
|
||||
Title:
|
President and Chief Executive Officer | |||
| AXCAN HOLDINGS INC. | ||||
By:
|
/s/ Xxxxx Xxxxxx | |||
Name:
|
||||
Title:
|
Senior VP, Chief Financial Officer and Treasurer | |||
| AXCAN LONE STAR INC. | ||||
By:
|
/s/ Xxxxx Xxxxxx | |||
Name:
|
||||
Title:
|
Senior VP, Chief Financial Officer and Treasurer | |||
