Exhibit 10.80 September 16, 1997 Mr. Randy M. Sloan 5203 Lexington Ridge Drive Lexington, MA 02173 Re: Amendment of Employment Agreement Dear Randy, This letter agreement serves to further amend the employment agreement dated as of October 1, 1996, by...

Exhibit 10.80
                                      September 16, 1997




Xx. Xxxxx X. Xxxxx
0000 Xxxxxxxxx Xxxxx Xxxxx
Xxxxxxxxx, XX   00000

                                      Re:  Amendment of Employment Agreement
Dear Xxxxx,

This letter agreement serves to further amend the employment  agreement dated as
of October 1, 1996,  by and between you and  PolyMedica  Industries,  Inc.  (the
"Company"),  as amended by a certain letter  agreement  dated as of July 1, 1997
(together, the "Employment Agreement").

         Term of  Employment.  The  Employment  Agreement  is hereby  amended to
         extend the Employment Period, as defined in Section 2 of the Employment
         Agreement, so that it ends on September 30, 1998.

If the foregoing is acceptable to you, please indicate your agreement by signing
a copy of this letter agreement and returning it to the undersigned.

                                      Very truly yours,


                                      /s/ Xxxxxx X. Xxx
                                      Xxxxxx X. Xxx
                                      Chairman and Chief Executive Officer


ACCEPTED AND AGREED TO:



/s/ Xxxxx X. Xxxxx
Xxxxx X. Xxxxx