Re: Amendment #6 to Consulting Agreement of July 12, 1999

June 25, 2009

Dr. Xxxx Xxxxxxxx

University of Xxxxxxxx

Xxxxxxxx, Xxxxxxx X0X 0X0

Xxxxxx

Re: Amendment #6 to Consulting Agreement of July 12, 1999

Dear Xx. Xxxxxxxx:

This will modify paragraph 11 of your Consulting Agreement with Senesco dated July 12, 1999, as modified.  Effective immediately, the term of the Consulting Agreement will be extended for an additional 2 year term through June 30, 2011.  All other terms of the Agreement remain unchanged.

Sincerely,

/s/ Xxxxx Xxxxxx

Xxxxx Xxxxxx

President

Senesco, Inc.

Acknowledged and Agreed:

/s/ Xxxx Xxxxxxxx

Dr. Xxxx Xxxxxxxx