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Contract Type FiledApril 21st, 2010Figure 3 The actin cytoskeleton mediates shape-induced terminal differentiation. (a, b) Quantification of involucrin expression after 24 h on substrates coated with type I collagen, fibronectin or laminin (a) and a high or low amount of total collagen (b; also see Supplementary Information, Fig. S2). Data represent means ± s.e.m. (n = 4 experiments). (c) Representative phase-contrast microscopy images of keratinocytes on islands with shape factors of 1, 2, 4 and 8. (d) Quantification of involucrin expression after 24 h