Common Contracts

Contract

October 23rd, 2014

• Filed
  October 23rd, 2014

Amendment #1 to Clinical Trial Agreement By and Between Aragon Pharmaceuticals, Inc, Pharmaceutical Research Associates CZ, s.r.o. and Fakultní nemocnice Olomouc For ARN-509-003 This Amendment #1 (the “Amendment #1 ) by and among ARAGON PHARMACEUTICALS, INC., with offices at located at 12780 El Camino Real, Suite 301, San Diego, CA 92130 ("Sponsor") and Fakultní nemocnice Olomouc, with offices located at I.P.Pavlova 185/6, 775 20 Olomouc, Czech Republic, company ID No.: 00098892, tax ID No.: CZ00098892, acting by prof. MUDr. Roman Havlík, Ph.D., director ("Institution") and Pharmaceutical Research Associates CZ, s.r.o. located at Jankovcova 1569/2c, 170 00 Praha 7, Czech Republic, Company ID No.: 276 36 852, Tax ID No.: CZ27636852, acting by MUDr. Andrea Klč, proxy (“PRA”), an affiliate of Pharmaceutical Research Associates, Inc, 4130 ParkLake Avenue, Suite 400, Raleigh, North Carolina 27612, USA (“PRA Inc. ”) is made and effective as of the date of execution that the last party