Common Contracts
2 similar Thesis contracts
License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of LeidenThesis • March 3rd, 2024
Acute renal failure (ARF) on the basis of acute tubular necrosis (ATN) was defined in the early days of the 20 th century by the German pathologist Hackstadt. His observations were based on the clinical evaluation of soldiers who sustained severe traumatic injury. However its significance was more or less neglected until the second world war, when Bywaters des- cribed the crush injury syndrome in victims of the London Blitz (1). Initially the underlying morphological changes in this kind of renal failure was thought to be related to distal tu- bular injury due to pigment toxicity and the term lower nephron nephrosis was introduced for this clinical condition (2). Later classic micro dissection studies in kidneys of rats showed that the dominant side of injury in ATN was the straight segment of the proximal tubules (S3 segment, pars recta) (3).
License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of LeidenThesis • July 13th, 2023
Acute renal failure (ARF) on the basis of acute tubular necrosis (ATN) was defined in the early days of the 20 th century by the German pathologist Hackstadt. His observations were based on the clinical evaluation of soldiers who sustained severe traumatic injury. However its significance was more or less neglected until the second world war, when Bywaters des- cribed the crush injury syndrome in victims of the London Blitz (1). Initially the underlying morphological changes in this kind of renal failure was thought to be related to distal tu- bular injury due to pigment toxicity and the term lower nephron nephrosis was introduced for this clinical condition (2). Later classic micro dissection studies in kidneys of rats showed that the dominant side of injury in ATN was the straight segment of the proximal tubules (S3 segment, pars recta) (3).
