ContractClinical Trial Agreement • March 9th, 2022
Contract Type FiledMarch 9th, 2022AMENDMENT NO. 2 TO CLINICAL TRIAL AGREEMENT This Amendment No. 2 to the Clinical Trial Agreement (“Amendment”) is made as of the latest date set forth on the signature page hereto by and among:Všeobecná fakultní nemocnice v Praze, having a place of business at U Nemocnice 499/2, 128 08 Praha 2, Czech Republic, identification number: 00064165, tax identification number: CZ00064165, represented by (the“Institution”) and (the “Investigator”), and Protalix Ltd., located at 2 Snunit Street, Science Park, P.O. Box 455, Carmiel 2161401, Israel (the “Sponsor”); And is effective as of its publication in the Register of Agreements but the Parties agree to be bound by the rights and obligations arising from this Amendment from 29 September 2021 (“Effective Date”). WITNESSETH:WHEREAS, Institution, Investigator and Sponsor (each, a “Party,” and collectively, the “Parties”) entered into that certain Clinical Trial Agreement as of 25 September 2019 as amended by Amendemnt No. 1 dated 17 June 2021 (th