Shared Care GuidelineShared Care Guideline • April 5th, 2021
Contract Type FiledApril 5th, 2021Ciclosporin for Rheumatology and Dermatology use (Adults) (Unlicensed use) Introduction This shared care agreement outlines the responsibilities between the specialist and the generalist for managing the prescribing of ciclosporin for unlicensed use in the indications listed below. Indication This is guidance for the unlicensed use of ciclosporin in the following conditions:• Rheumatic and connective tissue disease• Severe psoriasis in patients in whom conventional therapy is inappropriate or ineffective.• Other cutaneous disease Indications not covered by this shared care guideline:• Prevention of graft rejection (see separate shared care guideline from tertiary centre).• Endogenous uveitis• Nephrotic syndrome Dosage and administration For ALL indications patients should remain on the brand initiated and prescribing should be brand specific. Rheumatic and connective tissue disease Initiated at 1-2mg/kg day orally in two divided doses for six weeks (as per the Yorkshire DMARD gui
Shared Care GuidelineShared Care Guideline • November 13th, 2017
Contract Type FiledNovember 13th, 2017Ciclosporin for Rheumatology and Dermatology use (Adults) Introduction This shared care agreement outlines the responsibilities between the specialist and the generalist for managing the prescribing of ciclosporin for indications listed below. Indication • Rheumatic and connective tissue disease• Severe psoriasis in patients in whom conventional therapy is inappropriate or ineffective.• Other cutaneous disease Indications not covered by this shared care guideline:• Prevention of graft rejection (see separate shared care guideline from tertiary centre).• Endogenous uveitis• Nephrotic syndrome Dosage and administration For ALL indications patients should remain on the brand initiated and prescribing should be brand specific. Rheumatic and connective tissue disease Initiated at 1-2mg/kg day orally in two divided doses for six weeks (as per the Yorkshire DMARD guidelines) .Then increase every two weeks by incremental doses of 25mg until clinically effective. Maximum dose should not e