Shared Care GuidelineShared Care Guideline • April 5th, 2021
Contract Type FiledApril 5th, 2021Sulfasalazine (Adults) Introduction This shared care agreement outlines the responsibilities between the specialist and the generalist for managing the prescribing of sulfasalazine for indications listed below. Indication Rheumatoid arthritis, Crohn’s disease and ulcerative colitis. Unlicensed indications: Psoriatic arthritis, undifferentiated arthritis, spondyloarthropathies. Dosage and administration Rheumatoid arthritis:500mg daily for 1 week then 500mg twice daily for 1 week then 1g am, 500mg pm for 1 week then 1g twice daily (if gastric intolerance consider 500mg four times a day). If indicated the dose may be increased to 1.5g twice a day (max 40mg/kg/day). Gastroenterology indications: 1g-2g four times a day until remission occurs reducing to a maintenance dose of 500mg four times a day. Contraindications and cautions • Contra-indicated in hypersensitivity to sulfasalazine, its excipients, sulphonamides or salicylates (slow acetylator status).• Contra-indicated in patients