ContractClinical Trial Agreement • January 6th, 2023
Contract Type FiledJanuary 6th, 2023AMENDMENT NO. 1 TO CLINICAL TRIAL AGREEMENT This Amendment No 1 to the Clinical Trial Agreement (“Amendment”) is between: Fakultní nemocnice Ostrava, having a place of business at 17. listopadu 1790/5, 708 52 Ostrava- Poruba, Czech Republic, Identification number: 00843989, Tax identification number: CZ00843989, , Founding Deed of the Ministry of Health of the Czech Republic dated of November 25th, 1990, ref. No. OP-054-25.11.90 (the “Institution”), and (the “Investigator”), and IQVIA RDS Czech Republic, s.r.o., having a place of business at Pernerova 691/42, 186 00 Praha 8 - Karlín, Czech Republic, Identification number: 247 68 651, Tax identification number: CZ247 68 651, represented by Ing. Eva Falbrová, Managing Director (“IQVIA”), and HUYABIO International, LLC, having a place of business at 12531 High Bluff Drive, Suite 138, San Diego, CA2130, USA, Registration Number: 592553 (“Sponsor”) Each a “Party” and together the “Parties”. and is effective as of 27 May 2022 (“Effective Dat