Amendment # 2 to Clinical Trial Agreement Dodatek # 2 ke Smlouvě o provedení klinického hodnoceníClinical Trial Agreement • September 18th, 2017
Contract Type FiledSeptember 18th, 2017This Amendment # 2 (the “Amendment # 2” ) by and among ARAGON PHARMACEUTICALS, INC, with offices located at 12780 El Camino Real, Suite 301, San Diego, CA 92130 ("Sponsor") and Slezská nemocnice v Opavě, p.o., located at Olomoucká 86, 746 01, Opava, Czech Republic, ID number: 47813750, TAX ID number: CZ47813750, represented by MUDr. Ladislav Václavec, MBA, director (“Institution”) and Pharmaceutical Research Associates CZ, s.r.o. located at Jankovcova 1569/2c, 170 00 Praha 7, Czech Republic, Company ID No.: 276 36 852, Tax ID No.: CZ27636852, acting by MUDr. Andrea Klč, proxy (“PRA”), an affiliate of Pharmaceutical Research Associates, Inc, 4130 ParkLake Avenue, Suite 400, Raleigh, North Carolina 27612, USA (“PRA Inc.”), is made and effective as of the date of execution that the last party signs (hereinafter “Effective Date”). PRA has agreed to accept certain obligations and duties of PRA Inc. in respect of the conduct of the clinical trial in Czech Republic; Sponsor, PRA and Ins