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Common Contracts

2 similar License and Collaboration Agreement contracts by Isis Pharmaceuticals Inc

AMENDED AND RESTATED LICENSE AND COLLABORATION AGREEMENT
License and Collaboration Agreement • May 7th, 2009 • Isis Pharmaceuticals Inc • Pharmaceutical preparations • Delaware

This Amended and Restated License and Collaboration Agreement (the “Agreement”) is entered into as of the 1st day of January, 2009 (the “Amendment Effective Date”) by and among ALNYLAM PHARMACEUTICALS, INC., a Delaware corporation, with its principal place of business at 300 Third Street, Cambridge, Massachusetts 02142 (“Alnylam”), ISIS PHARMACEUTICALS, INC., a Delaware corporation, with its principal place of business at 1896 Rutherford Road, Carlsbad, California 92008 (“Isis”, and each of Alnylam and Isis, a “Licensor” and together, the “Licensors”), and REGULUS THERAPEUTICS INC. (formerly Regulus Therapeutics LLC), a Delaware corporation, with its principal place of business at 1896 Rutherford Road, Carlsbad, California 92008 (“Regulus”).

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LICENSE AND COLLABORATION AGREEMENT
License and Collaboration Agreement • November 9th, 2007 • Isis Pharmaceuticals Inc • Pharmaceutical preparations • Delaware

This License and Collaboration Agreement (the “License Agreement” or the “Agreement”) is entered into as of the 6th day of September 2007 (the “Effective Date”) by and among Alnylam Pharmaceuticals, Inc., a Delaware corporation, with its principal place of business at 300 Third Street, Cambridge, Massachusetts 02142 (“Alnylam”), Isis Pharmaceuticals, Inc., a Delaware corporation, with its principal place of business at 1896 Rutherford Road, Carlsbad, California 92008 (“Isis”, and each of Alnylam and Isis, a “Licensor” and together, the “Licensors”), and Regulus Therapeutics LLC, a Delaware limited liability company, with its principal place of business at 1896 Rutherford Road, Carlsbad, California 92008 (“Regulus”).