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Trial Agreement • July 24th, 2019

CLINICAL TRIAL AGREEMENT SMLOUVA O KLINICKÉM HODNOCENÍ Protocol # 1720302 Protokol číslo 1720302 This Clinical Trial Agreement (“Agreement”) is valid as of the date of last signature and effective of the date of its publishing in contract registry (“Effective Date”) by and between Tato smlouva o klinickém hodnocení (dále jen„smlouva“) je platná k datu připojení posledního podpisu a účinná dnem uveřejnění smlouvy v registru smluv (dále jen „datum účinnosti“) mezi Revance Therapeutics Inc, a Delaware corporation with a place of business at 7555 Gateway Boulevard, Newark, California 94560 USA (“Sponsor”) Revance Therapeutics Inc, Delaware corporation se sídlem 7555 Gateway Boulevard, Newark, California 94560 U.S.A. (dále jen „zadavatel“). and a Všeobecná fakultní nemocnice v Praze, with a place of business at U Nemocnice 499/2, 128 08 Praha 2, Czech Republic and with a Registration no.: 00064165, represented by , on the basis of the power of attorney(“Institution”) Všeobecná f

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