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Annex I - “Description of Work”*Grant Agreement • February 19th, 2016
The aim of this ITN is to take the category of Nonlinear Optical Microscopy (NOM) techniques into the nano-dimension, allowing for label-free three-dimensional (3D), dynamic imaging of macromolecular arrangements and nanostructures by probing inherent higher- order electronic and molecular vibrations with novel detection concepts. Specific S&T objectives are to (A) explore the use of nano-sized scanning probes, polarization or phase resolved detection schemes to enable nano-scale imaging, (B) benchmark their capabilities by fundamental studies and computations of molecular suprastructures and metallic nanostructures, and to (C) apply them in live-cell and fuel cell studies in order to introduce them as attractive instruments for the pharmaceutical-, nanotechnology-, and biosciences/industry. In particular, we will study (i) the formation of hierarchical structures of amyloid peptides and other biomolecules, (ii) nonlinear emission by metallic nanoparticles/holes/antennas as potential n
