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Confidential Czech Republic/Institution Only Clinical Trial Agreement
Clinical Trial Agreement • September 12th, 2019

CLINICAL TRIAL AGREEMENT This CLINICAL TRIAL AGREEMENT (the“Agreement”) is entered into and valid as of the last signature date below and effective as of the date of publication in the Registry of Contracts (described below in Article 21) (“EFFECTIVE DATE”) between Revmatologický ústav, state contributory organization, located at Na Slupi 450/4, 128 00 Praha 2 – Nové Město, Czech Republic, Company ID number (IČO): 00023728, VAT ID:CZ00023728, represented by prof. MUDr. Karel Pavelka, DrSc., director (the “Institution”), and Pharmaceutical Research Associates CZ, s.r.o., located at Praha 7, Jankovcova 1569/2c, Post Code (PSČ): 170 00, Czech Republic, IČ (company ID number): 27636852, the limited liability company duly registered in the Commercial Register of the Czech Republic maintained by the Municipal Court in Prague, Section C, Entry 120574, represented by xxxxxxxxxxx (“PRA”), an affiliate of Pharm Research Associates, (UK) Ltd., located at 500 Oak Way, Green Park, Reading, Berkshir

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