KEYWORDSPartnership License Agreement • February 1st, 2018
Contract Type FiledFebruary 1st, 2018Despite current effective and life-prolonging cART, HIV-1 can still not be cured. Indeed, the persistence of latently-infected resting CD4+ T cells harboring transcriptionally silent but replication competent HIV-1 proviruses seriously challenge the hope of HIV-1 eradication from cART-treated HIV-1 infected patients. Reactivation of HIV-1 expression in reservoirs together with an efficient cART has been pro- posed as an adjuvant therapy aimed at reaching a functional cure.