ContractInstitution Agreement • August 5th, 2022
Contract Type FiledAugust 5th, 2022AMENDMENT 2 TO STATEMENT OF AGREEMENT This Amendment 2 to Statement of Agreement (“Amendment 2”) is made as of the date of last signature, by and between: F. Hoffmann-La Roche Ltd with its registered office at Grenzacherstrasse 124, 4070 Basel, Switzerland (“Sponsor”), and PPD Investigator Services LLCwith its registered address at 929 North Front St, Wilmington, NC 28401, USAacting on its behalf and as an independent contractor on behalf of Sponsor (hereinafter referred to as the “PPD”) and Nemocnice Jihlava Vrchlického 59, 586 01 Jihlava, Czech Republic(hereinafter referred to as „ Institution”) andxxxwith his/her offices located at Vrchlického 59, 586 01 Jihlava, Czech Republic (“Investigator”) shall be an amendment to that certain Institution Agreement between Sponsor, PPD, Institution and Investigator dated 20th December 2021, and amendment No 1 dated 05th May 2022 (“Agreement”) for the Clinical trial xxx DODATEK Č. 2 KE SMLOUVĚ Tento Dodatek č. 2 ke Smlouvě (dále jen „Dodatek č.