0000109657-06-000042 Sample Contracts

AMENDMENT #2 TO EXCLUSIVE LICENSE AND SUPPLY AGREEMENT
Exclusive License and Supply Agreement • July 26th, 2006 • Oxis International Inc • Pharmaceutical preparations

This Amendment #2 to Exclusive License and Supply Agreement (“Amendment #2”) is made and entered into on the 19th day of July, 2006 (the “Effective Date”) by and between OXIS International, a Delaware corporation (“OXIS”), located at 6040 N. Cutter Circle, Suite 317, Portland, OR 97217 and HaptoGuard, Inc., a Delaware corporation, located at Park 80 West, Plaza II, Suite 200, Saddle Brook, NJ 07663 (“HaptoGuard”).

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OXIS INTERNATIONAL INC. COMMON STOCK PURCHASE WARRANT
Common Stock Purchase Warrant • July 26th, 2006 • Oxis International Inc • Pharmaceutical preparations • Delaware

This Warrant evidences the right to purchase an aggregate of 1,158,857 shares of Common Stock, subject to adjustment as provided in this Warrant.

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