0000874015-18-000060 Sample Contracts

LICENSE AGREEMENT
And License Agreement • May 7th, 2018 • Ionis Pharmaceuticals Inc • Pharmaceutical preparations • New York

THIS DEVELOPMENT, COMMERCIALIZATION, COLLABORATION, AND LICENSE AGREEMENT is made and entered into as of March 14, 2018 (the “Execution Date”), by and between Akcea Therapeutics, Inc., a Delaware corporation (“Akcea”), and Ionis Pharmaceuticals, Inc., a Delaware corporation (“Ionis”). Akcea and Ionis each may be referred to herein individually as a “Party,” or collectively as the “Parties.”

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IONIS PHARMACEUTICALS, INC. STRATEGIC ADVISORY SERVICES AGREEMENT (“SUMMARY PAGE”)
Advisory Services Agreement • May 7th, 2018 • Ionis Pharmaceuticals Inc • Pharmaceutical preparations • California

Duration of Strategic Advisory Services (the “Strategic Advisory Period”): Until termination by Ionis or Strategic Advisor in accordance with Section 8 of Exhibit A below.

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