0000874015-20-000115 Sample Contracts

AMENDMENT NO. 2
Ionis Pharmaceuticals Inc • August 5th, 2020 • Pharmaceutical preparations

This Amendment No. 2 (the “Amendment”) to the Strategic Collaboration Agreement dated July 31st, 2015, as previously amended by Amendment No. 1 dated October 18, 2018 (the “Agreement”), is made by and between

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