0000881464-12-000017 Sample Contracts

AMENDMENT TO COMMERCIAL SUPPLY AGREEMENT
Commercial Supply Agreement • August 3rd, 2012 • Amylin Pharmaceuticals Inc • Pharmaceutical preparations

This AMENDMENT TO COMMERCIAL SUPPLY AGREEMENT (the “Amendment”) is entered into as of April 17, 2012 (the “Amendment Effective Date”) by and between Amylin Pharmaceuticals, Inc. (“AMYLIN”), having a principal place of business at 9360 Towne Centre Drive, San Diego, CA 92121, and Bachem Americas, Inc. (“BACHEM”), having its principal place of business at 3132 Kashiwa Street, Torrance, CA 90505.

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SIXTH AMENDMENT TO EXENATIDE MANUFACTURING AGREEMENT
Exenatide Manufacturing Agreement • August 3rd, 2012 • Amylin Pharmaceuticals Inc • Pharmaceutical preparations

THIS SIXTH AMENDMENT to the Exenatide Manufacturing Agreement (the “Sixth Amendment”) originally made and entered into as of October 1, 2003, by and between Amylin Pharmaceuticals, Inc. (“AMYLIN”) and Mallinckrodt LLC (formerly known as Mallinckrodt Inc.) (“MALLINCKRODT”), as amended effective on and as of January 1, 2006, February 12, 2007, January 1, 2008, January 8, 2010 and February 14, 2011 (the “Supply Agreement”), is made and entered into between AMYLIN and MALLINCKRODT effective on and as of June 25, 2012 (except as and to the extent explicitly otherwise stated in this Sixth Amendment).

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