Exhibit 10.3 SECOND AMENDMENT TO THE ROYALTY AGREEMENT This Second Amendment, dated as of this 5th day of December 2002 (this "Second Amendment"), to the Royalty Agreement, dated as of December 26, 2000 (the "Royalty Agreement") is made by and between...Royalty Agreement • March 31st, 2003 • Cytomedix Inc • Services-commercial physical & biological research • Illinois
