EXHIBIT 4.1 FIRST AMENDMENT TO RIGHTS AGREEMENT This First Amendment to Rights Agreement dated as of October 3, 2000 (this "AMENDMENT"), to the Preferred Shares Rights Agreement dated as of September 19, 1997 (the "AGREEMENT"), is entered into by and...Rights Agreement • October 6th, 2000 • Innerdyne Inc • Services-commercial physical & biological research • New York
