EXHIBIT 10.22 CONFIDENTIAL PORTIONS HAVE BEEN OMITTED BASED UPON A REQUEST FOR CONFIDENTIAL TREATMENT PURSUANT TO RULE 24b-2 OF THE SECURITIES EXCHANGE ACT OF 1934 AND HAVE BEEN SEPARATELY FILED WITH THE COMMISSION AMENDED AND RESTATED LICENSE AND...License and Supply Agreement • November 15th, 1999 • Epoch Pharmaceuticals Inc • In vitro & in vivo diagnostic substances • California
