0000893220-05-001025 Sample Contracts

SECOND AMENDMENT TO RIGHTS AGREEMENT
Rights Agreement • May 4th, 2005 • Bone Care International Inc • Pharmaceutical preparations • Wisconsin

AMENDMENT, dated as of May 4, 2005 (this “Amendment”), between Bone Care International Inc., a Wisconsin corporation (the “Company”), and Wells Fargo Bank, N.A., as successor to Norwest Bank Minnesota, N.A. (the “Rights Agent”), to the Rights Agreement, dated as of April 15, 1996, as amended by the First Amendment to Rights Agreement, dated as of September 21, 1999, between the Company and the Rights Agent (collectively, the “Rights Agreement”).

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