0000893220-07-000790 Sample Contracts

AMENDED AND RESTATED RESEARCH, DEVELOPMENT AND LICENSE AGREEMENT AMONG NEOSE TECHNOLOGIES, INC. AND NOVO NORDISK A/S AND NOVO NORDISK HEALTH CARE AG DATED AS OF OCTOBER 31, 2006
Research, Development and License Agreement • March 16th, 2007 • Neose Technologies Inc • Medicinal chemicals & botanical products • Pennsylvania

This AMENDED AND RESTATED RESEARCH, DEVELOPMENT AND LICENSE AGREEMENT (“Agreement”), is dated as of October 31, 2006 (the “Restatement Date”), among Neose Technologies, Inc., a Delaware corporation (“Neose”), and Novo Nordisk A/S, a Danish corporation, and Novo Nordisk Health Care AG, a Swiss Corporation (collectively, “Novo”).

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Amendment Number 1 to Research, Co-Development and Commercialization Agreement and Research License and Option Agreement
Research, Co-Development and Commercialization Agreement and Research License and Option Agreement • March 16th, 2007 • Neose Technologies Inc • Medicinal chemicals & botanical products

This Amendment Number 1 (the “Amendment”) to the Collaboration Agreement and the License Agreement (both as defined below) is effective as of October 20, 2006 (the “Effective Date”), and is by and between BioGeneriX AG, a corporation organized under the laws of the Federal Republic of Germany (“BioGeneriX”), and Neose Technologies, Inc., a corporation organized and existing under the laws of the state of Delaware (“Neose”).

Agent (Name and Address) 10054613 AON Risk Services Inc. of PA One Liberty Place
Commercial Premium Finance Agreement • March 16th, 2007 • Neose Technologies Inc • Medicinal chemicals & botanical products • New York
Bioprocessing Services Agreement
Bioprocessing Services Agreement • March 16th, 2007 • Neose Technologies Inc • Medicinal chemicals & botanical products • New York

This Bioprocessing Services Agreement dated this 7th day of December, 2006 (the “Effective Date”) is between Neose Technologies, Inc., a Delaware corporation (“Neose”) having its principal place of business at 102 Witmer Road, Horsham, PA, 19044 and Diosynth RTP Inc., a Delaware corporation (“Diosynth”), having its principal place of business at 101 J. Morris Commons Lane, Morrisville, NC 27560, (each a “Party”, collectively, the “Parties”).

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