EXHIBIT 2.1(b) FIRST AMENDMENT TO AGREEMENT AND PLAN OF MERGER THIS FIRST AMENDMENT TO AGREEMENT AND PLAN OF MERGER (the "Amendment") is dated as of October 7, 2005, by and among Cougar Biotechnology, Inc., a Delaware corporation ("Cougar"), GVC...Agreement and Plan of Merger • October 11th, 2005 • GVC Venture Corp • Non-operating establishments
