EXHIBIT 4.1 NEOTHERAPEUTICS, INC. SECURITIES PURCHASE AGREEMENTSecurities Purchase Agreement • May 25th, 2000 • Neotherapeutics Inc • Services-commercial physical & biological research • California
EXHIBIT 4.2 REGISTRATION RIGHTS AGREEMENT This Registration Rights Agreement (this "AGREEMENT") is made and entered into as of April 28, 2000, among NeoTherapeutics, Inc., a Delaware corporation (the "COMPANY"), and the investors signatory hereto...Registration Rights Agreement • May 25th, 2000 • Neotherapeutics Inc • Services-commercial physical & biological research • California
May 1, 2000 Royal Canadian Growth Fund c/o Royal Bank Investment Management, Inc. 77 King St. West Royal Trust Tower, Suite 3800 Toronto, Ontario M5K 1H1 Attention: Eden Rahim Re: NEOTHERAPEUTICS, INC. (THE "COMPANY"). Gentlemen: Reference is made to...Securities Purchase Agreement • May 25th, 2000 • Neotherapeutics Inc • Services-commercial physical & biological research
Royal Canadian Growth Fund c/o Royal Bank Investment Management, Inc. 77 King St. West Royal Trust Tower, Suite 3800 Toronto, Ontario M5K 1H1 Attention: Eden Rahim
