0000912057-01-515377 Sample Contracts

INDUSTRIAL LEASE AGREEMENT GRAND/ROEBLING INVESTMENT COMPANY a California limited partnership LANDLORD and SHAMAN PHARMACEUTICALS, INC. a California corporation TENANT EFFECTIVE DATE OF EXECUTION: January 1, 1993
Industrial Lease Agreement • May 14th, 2001 • Tularik Inc • Pharmaceutical preparations • California

Real Property: Parcels 1, 2 and 3, more particularly described in Exhibit "B-1" attached hereto and incorporated herein by reference, known as San Mateo County Assessor Parcel Numbers 015-041-270 and 015-041-200 (together, the "Real Property"). A Plot Plan outlining the Real Property, the location of the three (3) Buildings site on the Real Property, and the Easement and Driveway (referenced below) is attached hereto as Exhibit "A" and incorporated herein by reference.

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THIRD AMENDMENT TO LEASE
Lease Agreement • May 14th, 2001 • Tularik Inc • Pharmaceutical preparations

This THIRD AMENDMENT TO LEASE (this "Amendment") is dated as of this 27th day of March, 2001 by and between GRAND/ROEBLING INVESTMENT COMPANY, a California limited partnership ("Landlord") and TULARIK INC., a Delaware corporation ("Tenant").

ASSIGNMENT OF LEASE
Assignment of Lease • May 14th, 2001 • Tularik Inc • Pharmaceutical preparations

THIS ASSIGNMENT (the "Assignment"), dated as of this 27th day of March, 2001, is made between Shaman Pharmaceuticals, Inc., a Delaware corporation, ("Assignor") and Tularik Inc., a Delaware corporation ("Assignee"), with reference to the following:

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